Airway inflammation in adolescents and elderly women: Chronic air pollution exposure and polygenic susceptibility
S Kress, A Kilanowski, C Wigmann, Q Zhao… - Science of The Total …, 2022 - Elsevier
Background and aim The fractional exhaled nitric oxide (FeNO) concentration in the exhaled
breath is a biomarker for eosinophilic airway inflammation. We explored the interplay …
breath is a biomarker for eosinophilic airway inflammation. We explored the interplay …
Air pollution, metabolites and respiratory health across the life-course
Previous studies have explored the relationships of air pollution and metabolic profiles with
lung function. However, the metabolites linking air pollution and lung function and the …
lung function. However, the metabolites linking air pollution and lung function and the …
[HTML][HTML] Evaluation of tree-based statistical learning methods for constructing genetic risk scores
M Lau, C Wigmann, S Kress, T Schikowski… - BMC …, 2022 - Springer
Background Genetic risk scores (GRS) summarize genetic features such as single nucleotide
polymorphisms (SNPs) in a single statistic with respect to a given trait. So far, GRS are …
polymorphisms (SNPs) in a single statistic with respect to a given trait. So far, GRS are …
[HTML][HTML] Does social cohesion mediate neighbourhood effects on mental and physical health? Longitudinal analysis using German Socio-Economic Panel data
S Kress, O Razum, KA Zolitschka, J Breckenkamp… - BMC public health, 2020 - Springer
Background Neighbourhood has risen as a relevant determinant of health. While there is
substantial evidence that environmental factors affect health, far less evidence of the role of …
substantial evidence that environmental factors affect health, far less evidence of the role of …
Allergic disease trajectories up to adolescence: Characteristics, early‐life, and genetic determinants
A Kilanowski, E Thiering, G Wang, A Kumar, S Kress… - Allergy, 2023 - Wiley Online Library
Background Allergic diseases often develop jointly during early childhood but differ in timing
of onset, remission, and progression. Their disease course over time is often difficult to …
of onset, remission, and progression. Their disease course over time is often difficult to …
[HTML][HTML] Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility
S Kress, C Wigmann, Q Zhao, C Herder… - Respiratory …, 2022 - Springer
Background Air pollutants can activate low-grade subclinical inflammation which further impairs
respiratory health. We aimed to investigate the role of polygenic susceptibility to chronic …
respiratory health. We aimed to investigate the role of polygenic susceptibility to chronic …
[HTML][HTML] European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide
association studies (GWAS) have identified 71 associated loci. In the current study we conducted …
association studies (GWAS) have identified 71 associated loci. In the current study we conducted …
[HTML][HTML] A gene variant of AKR1C3 contributes to interindividual susceptibilities to atopic dermatitis triggered by particulate air pollution
The pathogenesis of atopic dermatitis (AD) involves an impairment of the skin barrier by an
interplay of genetic and environmental factors. The resulting inappropriate defense against …
interplay of genetic and environmental factors. The resulting inappropriate defense against …
[HTML][HTML] Air pollution during infancy and lung function development into adolescence: The GINIplus/LISA birth cohorts study
Q Zhao, S Kress, I Markevych, D Berdel… - Environment …, 2021 - Elsevier
Background Limited evidence exists on how air pollution exposure during infancy, ie the
first year of life, may affect lung function development into adolescence. Objectives To …
first year of life, may affect lung function development into adolescence. Objectives To …
Changes in sleep duration and sleep difficulties from adolescence to young adulthood and the risk of obesity: bidirectional evidence in the GINIplus and LISA studies
M Wang, C Flexeder, A Kilanowski, S Kress… - Sleep Medicine, 2023 - Elsevier
Objective This study aimed to assess the association of changes in sleep behaviors from
adolescence to young adulthood with the risk of overweight/obesity, and the reverse …
adolescence to young adulthood with the risk of overweight/obesity, and the reverse …