Airway inflammation in adolescents and elderly women: Chronic air pollution exposure and polygenic susceptibility

S Kress, A Kilanowski, C Wigmann, Q Zhao… - Science of The Total …, 2022 - Elsevier
Background and aim The fractional exhaled nitric oxide (FeNO) concentration in the exhaled
breath is a biomarker for eosinophilic airway inflammation. We explored the interplay …

Air pollution, metabolites and respiratory health across the life-course

…, J de Bont, MGM Pinho, IC Eze, S Kress… - European respiratory …, 2022 - Eur Respiratory Soc
Previous studies have explored the relationships of air pollution and metabolic profiles with
lung function. However, the metabolites linking air pollution and lung function and the …

[HTML][HTML] Evaluation of tree-based statistical learning methods for constructing genetic risk scores

M Lau, C Wigmann, S Kress, T Schikowski… - BMC …, 2022 - Springer
Background Genetic risk scores (GRS) summarize genetic features such as single nucleotide
polymorphisms (SNPs) in a single statistic with respect to a given trait. So far, GRS are …

[HTML][HTML] Does social cohesion mediate neighbourhood effects on mental and physical health? Longitudinal analysis using German Socio-Economic Panel data

S Kress, O Razum, KA Zolitschka, J Breckenkamp… - BMC public health, 2020 - Springer
Background Neighbourhood has risen as a relevant determinant of health. While there is
substantial evidence that environmental factors affect health, far less evidence of the role of …

Allergic disease trajectories up to adolescence: Characteristics, early‐life, and genetic determinants

A Kilanowski, E Thiering, G Wang, A Kumar, S Kress… - Allergy, 2023 - Wiley Online Library
Background Allergic diseases often develop jointly during early childhood but differ in timing
of onset, remission, and progression. Their disease course over time is often difficult to …

[HTML][HTML] Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility

S Kress, C Wigmann, Q Zhao, C Herder… - Respiratory …, 2022 - Springer
Background Air pollutants can activate low-grade subclinical inflammation which further impairs
respiratory health. We aimed to investigate the role of polygenic susceptibility to chronic …

[HTML][HTML] European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

…, J Fadista, CA Wang, E Thiering, B Wu, S Kress… - Nature …, 2023 - nature.com
Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide
association studies (GWAS) have identified 71 associated loci. In the current study we conducted …

[HTML][HTML] A gene variant of AKR1C3 contributes to interindividual susceptibilities to atopic dermatitis triggered by particulate air pollution

C Vogeley, S Kress, D Lang, CFA Vogel, F Hartung… - Allergy, 2023 - ncbi.nlm.nih.gov
The pathogenesis of atopic dermatitis (AD) involves an impairment of the skin barrier by an
interplay of genetic and environmental factors. The resulting inappropriate defense against …

[HTML][HTML] Air pollution during infancy and lung function development into adolescence: The GINIplus/LISA birth cohorts study

Q Zhao, S Kress, I Markevych, D Berdel… - Environment …, 2021 - Elsevier
Background Limited evidence exists on how air pollution exposure during infancy, ie the
first year of life, may affect lung function development into adolescence. Objectives To …

Changes in sleep duration and sleep difficulties from adolescence to young adulthood and the risk of obesity: bidirectional evidence in the GINIplus and LISA studies

M Wang, C Flexeder, A Kilanowski, S Kress… - Sleep Medicine, 2023 - Elsevier
Objective This study aimed to assess the association of changes in sleep behaviors from
adolescence to young adulthood with the risk of overweight/obesity, and the reverse …