Background: Pulmonary rehabilitation is recognized as a core component of the management
of individuals with chronic respiratory disease. Since the 2006 American Thoracic Society (…

Background: Pulmonary rehabilitation has become a standard of care for patients with
chronic lung diseases. This document provides a systematic, evidence-based review of the …

Background Acute exacerbations adversely affect patients with chronic obstructive pulmonary
disease (COPD). Macrolide antibiotics benefit patients with a variety of inflammatory …

Background Athletes often take androgenic steroids in an attempt to increase their strength.
The efficacy of these substances for this purpose is unsubstantiated, however. Methods We …

… Casaburi, AL Coates, PL Enright, JL Hankinson, CG Irvin, NR MacIntyre, RT McKay, JS
Wanger, SD Anderson, DW Cockcroft, JE Fish, PJ Sterk …

Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance, …

Though exercise training is part of most pulmonary rehabilitation programs, whether there is
a physiologic basis for increased exercise tolerance is unclear. We sought to determine …

Testosterone increases muscle mass and strength and regulates other physiological processes,
but we do not know whether testosterone effects are dose dependent and whether dose …

Rationale: Pulmonary rehabilitation (PR) has demonstrated physiological, symptom-reducing,
psychosocial, and health economic benefits for patients with chronic respiratory diseases, …

In patients with pulmonary disease, disease severity and prognosis are determined not only
by lung function impairment (1, 2). In patients with mild, moderate, or severe disease, …