User profiles for R. Saggar
Rajan SaggarUniversity of California Los Angeles Verified email at mednet.ucla.edu Cited by 8426 |
Pulmonary vascular hemodynamic response to exercise in cardiopulmonary diseases
… where R 0 is PVR and Q is pulmonary blood flow. The distensibility coefficient α defines how
much resistance vessel diameters increase as a percent of baseline per mmHg distending …
much resistance vessel diameters increase as a percent of baseline per mmHg distending …
Exercise-induced pulmonary hypertension: physiological basis and methodological concerns
…, BP Dhakal, R Saggar, R Saggar… - American journal of …, 2013 - atsjournals.org
… where R 0 is total pulmonary vascular resistance. This equation is more complicated than
the traditional PVR equation, and an α of 2%/mm Hg pressure may not seem substantial. We …
the traditional PVR equation, and an α of 2%/mm Hg pressure may not seem substantial. We …
Diagnosis and treatment of pulmonary sarcoidosis: a review
Importance Sarcoidosis is an inflammatory granulomatous disease of unknown cause that
affects an estimated 2 to 160 people per 100 000 worldwide and can involve virtually any …
affects an estimated 2 to 160 people per 100 000 worldwide and can involve virtually any …
[HTML][HTML] Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
…, SO Vargas, R Saggar, R Saggar… - The Journal of …, 2016 - Am Soc Clin Investig
Dysregulation of vascular stiffness and cellular metabolism occurs early in pulmonary
hypertension (PH). However, the mechanisms by which biophysical properties of the vascular …
hypertension (PH). However, the mechanisms by which biophysical properties of the vascular …
Right ventricular dysfunction in systemic sclerosis–associated pulmonary arterial hypertension
…, SD Russell, R Saggar, R Saggar… - Circulation: Heart …, 2013 - Am Heart Assoc
… decline for any corresponding R PA , shifting the R PA -C PA … principally on factors that
influence mean R PA . The small but … Our prior analysis also showed no change in the R PA -C PA …
influence mean R PA . The small but … Our prior analysis also showed no change in the R PA -C PA …
[HTML][HTML] Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension
Development of the vascular disease pulmonary hypertension (PH) involves disparate
molecular pathways that span multiple cell types. MicroRNAs (miRNAs) may coordinately …
molecular pathways that span multiple cell types. MicroRNAs (miRNAs) may coordinately …
Tuberculous osteomyelitis
…, S Dogra, RR Saggar, R Sharma - The Journal of Bone …, 1997 - boneandjoint.org.uk
Tuberculous osteomyelitis which does not involve a joint is uncommon and may fail to be
diagnosed by an orthopaedic surgeon. We treated 28 lesions of tuberculous osteomyelitis in …
diagnosed by an orthopaedic surgeon. We treated 28 lesions of tuberculous osteomyelitis in …
An official European Respiratory Society statement: pulmonary haemodynamics during exercise
…, A Peacock, S Rosenkranz, R Saggar… - European …, 2017 - Eur Respiratory Soc
There is growing recognition of the clinical importance of pulmonary haemodynamics during
exercise, but several questions remain to be elucidated. The goal of this statement is to …
exercise, but several questions remain to be elucidated. The goal of this statement is to …
[PDF][PDF] Matrix remodeling promotes pulmonary hypertension through feedback mechanoactivation of the YAP/TAZ-miR-130/301 circuit
Pulmonary hypertension (PH) is a deadly vascular disease with enigmatic molecular origins.
We found that vascular extracellular matrix (ECM) remodeling and stiffening are early and …
We found that vascular extracellular matrix (ECM) remodeling and stiffening are early and …
[HTML][HTML] Right ventricular systolic pressure by echocardiography as a predictor of pulmonary hypertension in idiopathic pulmonary fibrosis
RATIONALE: Pulmonary hypertension (PH) commonly complicates the course of patients with
idiopathic pulmonary fibrosis (IPF). It has a significant impact on outcomes and is, therefore…
idiopathic pulmonary fibrosis (IPF). It has a significant impact on outcomes and is, therefore…