Roach, Robert C., Peter H. Hackett, Oswald Oelz, Peter Bärtsch, Andrew M. Luks, Martin J.
MacInnis, J. Kenneth Baillie, and The Lake Louise AMS Score Consensus Committee. The …

Background. Exaggerated pulmonary-artery pressure due to hypoxic vasoconstriction is
considered an important pathogenetic factor in high-altitude pulmonary edema. We previously …

Key Clinical Points Acute High-Altitude Illnesses Acute high-altitude illnesses occur in persons
who are not acclimatized during the first days at an altitude of 2500 m or higher, with wide …

The increase in heart rate is related to increased sympathetic activity and vagal withdrawal.
10 For a given level of exercise, heart rate is greater at altitude11 (Figure 2), although the …

OBJECTIVE: To determine the safety and efficacy of an exercise protocol designed to improve
strength, mobility, and balance and to reduce subsequent falls in geriatric patients with a …

Background Pulmonary hypertension is a hallmark of high-altitude pulmonary edema and
may contribute to its pathogenesis. When administered by inhalation, nitric oxide, an …

High-altitude pulmonary edema (HAPE) develops in rapidly ascending nonacclimatized
healthy individuals at altitudes above 3,000 m. An excessive rise in pulmonary artery pressure (…

Background: High-altitude pulmonary edema (HAPE) is caused by exaggerated hypoxic
pulmonary vasoconstriction associated with decreased bioavailability of nitric oxide in the lungs …

At any point 1–5 days following ascent to altitudes ≥2500 m, individuals are at risk of
developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of …

ContextThe pathogenesis of high-altitude pulmonary edema (HAPE) is considered an
altered permeability of the alveolar-capillary barrier secondary to intense pulmonary …