Background To inform the development of the European Academy of Allergy and Clinical
Immunology's ( EAACI ) Guidelines on Allergen Immunotherapy ( AIT ) for allergic asthma, we …

In less than half a century, allergy, originally perceived as a rare disease, has become a
major public health threat, today affecting the lives of more than 60 million people in Europe, …

Background Allergic rhinitis (AR) is increasingly acknowledged as having a substantial
socioeconomic impact associated with impaired work productivity, although available information …

Inflammation, structural, and functional abnormalities within the airways are key features of
asthma. Although these processes are well documented, their expression varies across the …

It is well recognized that atopic sensitization is an important risk factor for asthma, both in
adults and in children. However, the role of allergy in severe asthma is still under debate. The …

An imbalance between the production of reactive oxygen species and the capacity of
antioxidant defense mechanisms favoring oxidants is called oxidative stress and is implicated in …

Reactive oxygen species (ROS) are produced by living organisms as a result of normal
cellular metabolism and environmental factors, such as air pollutants or cigarette smoke. ROS …

Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …

Allergic rhinitis (AR) and asthma represent global health problems for all age groups.
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on …

The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease
and depends on many factors. Grading of Recommendations Assessment, Development …