SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells
The SARS ‐CoV‐2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID ‐19 …
public health and urgently demands for increasing our understanding of COVID ‐19 …
Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo …
…, M Frankenberger, S Hummler, N Kahn… - The Lancet …, 2021 - thelancet.com
Background Pirfenidone has been shown to slow disease progression in patients with
idiopathic pulmonary fibrosis (IPF). However, there are few treatment options for progressive …
idiopathic pulmonary fibrosis (IPF). However, there are few treatment options for progressive …
Combined endoscopic-endobronchial ultrasound-guided fine-needle aspiration of mediastinal lymph nodes through a single bronchoscope in 150 patients with …
FJF Herth, M Krasnik, N Kahn, R Eberhardt, A Ernst - Chest, 2010 - Elsevier
… Author links open overlay panel Felix JF Herth MD, FCCP a , Mark Krasnik MD b , Nicolas
Kahn MD a , Ralf … Dr Kahn: participated in the design of the study and performed procedures. …
Kahn MD a , Ralf … Dr Kahn: participated in the design of the study and performed procedures. …
The therapy of idiopathic pulmonary fibrosis: what is next?
…, N Chaudhuri, SE Torrisi, N Kahn… - European …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung disease,
characterised by progressive scarring of the lung and associated with a high burden of …
characterised by progressive scarring of the lung and associated with a high burden of …
Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: long-term results of the …
…, J Kirschner, S Gläser, N Kahn… - European …, 2020 - Eur Respiratory Soc
Objective There is a paucity of observational data on antifibrotic therapy for idiopathic pulmonary
fibrosis (IPF). We aimed to assess the course of disease of IPF patients with and without …
fibrosis (IPF). We aimed to assess the course of disease of IPF patients with and without …
Fibroblast activation protein–specific PET/CT imaging in fibrotic interstitial lung diseases and lung cancer: a translational exploratory study
…, O Weinheimer, P Flechsig, N Kahn… - Journal of nuclear …, 2022 - Soc Nuclear Med
Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among
them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are associated with a poor …
them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are associated with a poor …
[HTML][HTML] LungPoint—a new approach to peripheral lesions
R Eberhardt, N Kahn, D Gompelmann… - Journal of thoracic …, 2010 - Elsevier
Introduction: Although flexible bronchoscopy is the least invasive procedure for sampling, it
is limited by its inability to reach lesions in the peripheral segments of the lung. Biopsy …
is limited by its inability to reach lesions in the peripheral segments of the lung. Biopsy …
Pirfenidone in idiopathic pulmonary fibrosis: real-life experience from a German tertiary referral center for interstitial lung diseases
U Oltmanns, N Kahn, K Palmowski, A Träger, H Wenz… - Respiration, 2014 - karger.com
Background: Pirfenidone is a novel antifibrotic drug for the treatment of mild-to-moderate
idiopathic pulmonary fibrosis (IPF). However, adverse events may offset treatment benefits and …
idiopathic pulmonary fibrosis (IPF). However, adverse events may offset treatment benefits and …
Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease
…, S Hirtz, R Agrawal, T Muley, N Kahn… - American journal of …, 2015 - atsjournals.org
Rationale: In many organs, hypoxic cell death triggers sterile neutrophilic inflammation via IL-1R
signaling. Although hypoxia is common in airways from patients with cystic fibrosis (CF), …
signaling. Although hypoxia is common in airways from patients with cystic fibrosis (CF), …
[HTML][HTML] The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time: longitudinal data from the INSIGHTS-IPF registry
…, JF Meyer, J Kirschner, S Gläser, N Kahn… - Respiratory …, 2019 - Springer
Background Quality of life (QoL) is profoundly impaired in patients with idiopathic pulmonary
fibrosis (IPF). However, data is limited regarding the course of QoL. We therefore analysed …
fibrosis (IPF). However, data is limited regarding the course of QoL. We therefore analysed …