[HTML][HTML] Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective

…, P Dorfmüller, MG Frid, G Butrous, NW Morrell… - Nature Reviews …, 2022 - nature.com
The lungs are the primary target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection, with severe hypoxia being the cause of death in the most critical cases. …

Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension

…, SD Moore, PD Upton, NW Morrell… - Cardiovascular …, 2022 - academic.oup.com
Aims Endothelial cell (EC) dysfunction drives the initiation and pathogenesis of pulmonary
arterial hypertension (PAH). We aimed to characterize EC dynamics in PAH at single-cell …

Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis

…, J Davies, IP Horan, NW Morrell… - British journal of …, 2017 - Wiley Online Library
Background and Purpose Group III pulmonary hypertension (PH) is a highly lethal and
widespread lung disorder that is a common complication in idiopathic pulmonary fibrosis (IPF) …

The integrated stress response in pulmonary disease

…, N Nassehzadeh-Tabriz, NW Morrell… - European …, 2020 - Eur Respiratory Soc
The respiratory tract and its resident immune cells face daily exposure to stress, both from
without and from within. Inhaled pathogens, including severe acute respiratory syndrome …

miR‐322‐5p targets IGF‐1 and is suppressed in the heart of rats with pulmonary hypertension

M Connolly, BE Garfield, A Crosby, NW Morrell… - FEBS Open …, 2018 - Wiley Online Library
Pulmonary arterial hypertension ( PAH ) is characterised by remodelling of the pulmonary
vasculature leading to right ventricular hypertrophy. Here, we show that miR‐322‐5p (the …

[BOOK][B] Pulmonary circulation: From basic mechanisms to clinical practice

JMB Hughes, NW Morrell - 2001 - books.google.com
This new book with 35 chapters is a comprehensive account of the important features of the
pulmonary circulation which will appeal to (1) clinical and non-clinical students who want a …

[HTML][HTML] miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension

M Connolly, BE Garfield, A Crosby, NW Morrell… - PLoS …, 2020 - journals.plos.org
The microRNA miR-1 is an important regulator of muscle phenotype including cardiac muscle.
Down-regulation of miR-1 has been shown to occur in left ventricular hypertrophy but its …

The UK National Cohort Study of idiopathic and heritable pulmonary arterial hypertension

…, MR Wilkins, SJ Wort, S Graf, NW Morrell - D54. CLINICAL …, 2016 - atsjournals.org
Methods Incident and prevalent cases of heritable and idiopathic PAH are being recruited
from the 7 national UK pulmonary hypertension centres, initially over a 5 year period. …

[HTML][HTML] Measurement of 139La(p,x) cross sections from 35–60 MeV by stacked-target activation

JT Morrell, AS Voyles, MS Basunia… - The European Physical …, 2020 - Springer
A stacked-target of natural lanthanum foils (99.9119% 139 La) was irradiated using a 60 MeV
proton beam at the LBNL 88-Inch Cyclotron. La(p,x) cross sections are reported between …

Secondary neutron production from thick target deuteron breakup

JT Morrell, AS Voyles, JC Batchelder, JA Brown… - Physical Review C, 2023 - APS
Thick target deuteron breakup is a variable-energy accelerator-based source of high-energy
neutrons, with applications in fundamental and applied nuclear science and engineering. …