Sarcoidosis is characterised by non-caseating granulomas that secrete pro-inflammatory
cytokines, including interleukin (IL)-12, IL-23, and tumour necrosis factor (TNF)-α. Ustekinumab …

Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and
function remain incompletely characterized. Purpose To test whether SARS-CoV-2 infection …

Current hypotheses of the pathogenesis of many forms of pulmonary fibrosis suggest that (i)
a stimulus results in repeated or prolonged episodes of lung injury, and (ii) genetic factors …

Background No formal guidelines exist to guide physicians caring for patients with sarcoidosis
in their screening for management of patients with cardiac sarcoidosis. We conducted a …

Pulmonary sarcoidosis presents substantial management challenges, with limited evidence
on effective therapies and phenotypes. In the absence of definitive evidence, expert …

Sarcoidosis is a multisystem disease with tremendous heterogeneity in disease manifestations,
severity, and clinical course that varies among different ethnic and racial groups. To …

Cardiac involvement affects ≤40% of patients with sarcoidosis and accounts for ≤25% of
deaths. The diagnosis of cardiac sarcoidosis is challenging using the existing screening tests …

Objective Cardiac sarcoidosis is difficult to diagnose, often requiring expensive and inconvenient
advanced imaging techniques. Circulating exosomes contain genetic material, such as …

Sarcoidosis is a complex systemic disease. Our study aimed to (1) identify novel alleles
associated with sarcoidosis susceptibility; (2) provide an in-depth evaluation of HLA alleles and …

The contribution and regulation of various CD4 + T cell lineages that occur with remitting vs
progressive courses in sarcoidosis are poorly understood. We developed a multiparameter …