Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension

…, S Kreuscher, S Ghofrani, MM Hoeper, M Halank… - Circulation, 2006 - Am Heart Assoc
Background— Pulmonary hypertension (PH) is associated with restricted physical capacity,
limited quality of life, and a poor prognosis because of right heart failure. The present study …

Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers

…, ZC Jing, C Opitz, HJ Seyfarth, M Halank… - Journal of the American …, 2006 - jacc.org
Objectives : This study sought to assess the risks associated with right heart catheter
procedures in patients with pulmonary hypertension. Background : Right heart catheterization, …

Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry

…, E Grunig, G Staehler, S Rosenkranz, M Halank… - International journal of …, 2013 - Elsevier
Background Originally reported to occur predominantly in younger women, idiopathic pulmonary
arterial hypertension (IPAH) is increasingly diagnosed in elderly patients. We aimed to …

Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension

C Rubens, R Ewert, M Halank, R Wensel… - Chest, 2001 - Elsevier
Study objectives Primary pulmonary hypertension (PPH) is a rare disease of unknown
etiology that is characterized by a poor prognosis. This study was undertaken to investigate …

Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary …

…, E Grünig, G Staehler, S Rosenkranz, M Halank… - Circulation, 2014 - Am Heart Assoc
Background— For almost 30 years, anticoagulation has been recommended for patients with
idiopathic pulmonary arterial hypertension (IPAH). Supporting evidence, however, is limited…

[HTML][HTML] COMPERA 2.0: a refined four-stratum risk assessment model for pulmonary arterial hypertension

…, J Behr, K Milger, M Halank… - European …, 2022 - Eur Respiratory Soc
Background Risk stratification plays an essential role in the management of patients with
pulmonary arterial hypertension (PAH). The current European guidelines propose a three-…

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study

HA Ghofrani, MM Hoeper, M Halank… - European …, 2010 - Eur Respiratory Soc
We assessed the therapeutic potential of riociguat, a novel soluble guanylate cyclase
stimulator, in adults with chronic thromboembolic pulmonary hypertension (CTEPH; n = 42) or …

Safety and efficacy of exercise training in various forms of pulmonary hypertension

…, F Reichenberger, G Staehler, M Halank… - European …, 2012 - Eur Respiratory Soc
The objective of this prospective study was to assess safety and efficacy of exercise training
in a large cohort of patients with different forms and World Health Organization (WHO) …

Exercise training improves peak oxygen consumption and haemodynamics in patients with severe pulmonary arterial hypertension and inoperable chronic thrombo …

…, R Nechwatal, S Uiker, M Halank… - European heart …, 2016 - academic.oup.com
Aims The impact of exercise training on the right heart and pulmonary circulation has not yet
been invasively assessed in patients with pulmonary hypertension (PH) and right heart …

Pulmonary hypertension due to lung diseases: Updated recommendations from the Cologne Consensus Conference 2018

…, H Bremer, M Claussen, P Douschan, M Halank… - International journal of …, 2018 - Elsevier
The 2015 European Guidelines on Pulmonary Hypertension did not only cover pulmonary
arterial hypertension (PAH) but also some aspects of pulmonary hypertension (PH) …