User profiles for Megan Shaw

Megan L. Shaw

- Verified email at uwc.ac.za - Cited by 6889

Megan Shaw

- Verified email at princeton.edu - Cited by 5301

Photoredox catalysis in organic chemistry

MH Shaw, J Twilton… - The Journal of organic …, 2016 - ACS Publications
In recent years, photoredox catalysis has come to the forefront in organic chemistry as a
powerful strategy for the activation of small molecules. In a general sense, these approaches …

The merger of transition metal and photocatalysis

J Twilton, C Le, P Zhang, MH Shaw, RW Evans… - Nature Reviews …, 2017 - nature.com
The merger of transition metal catalysis and photocatalysis, termed metallaphotocatalysis,
has recently emerged as a versatile platform for the development of new, highly enabling …

Human host factors required for influenza virus replication

…, A García-Sastre, JAT Young, P Palese, ML Shaw… - Nature, 2010 - nature.com
Influenza A virus is an RNA virus that encodes up to 11 proteins and this small coding capacity
demands that the virus use the host cellular machinery for many aspects of its life cycle 1 . …

Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose

…, C Riou, AD Sutherland, T Suliman, ML Shaw… - The Lancet, 2022 - thelancet.com
A group of German visitors who had received three doses of SARS-CoV-2 vaccines, including
at least two doses of an mRNA vaccine, experienced breakthrough infections with omicron …

[PDF][PDF] Meta-and orthogonal integration of influenza “OMICs” data defines a role for UBR4 in virus budding

…, E Verschueren, D Sanders, N Krogan, M Shaw… - Cell host & …, 2015 - cell.com
Several systems-level datasets designed to dissect host-pathogen interactions during influenza
A infection have been reported. However, apparent discordance among these data has …

Native functionality in triple catalytic cross-coupling: sp3 C–H bonds as latent nucleophiles

MH Shaw, VW Shurtleff, JA Terrett, JD Cuthbertson… - Science, 2016 - science.org
The use of sp 3 C–H bonds—which are ubiquitous in organic molecules—as latent nucleophile
equivalents for transition metal–catalyzed cross-coupling reactions has the potential to …

Ebola virus VP24 binds karyopherin α1 and blocks STAT1 nuclear accumulation

…, LW Leung, AL Hartman, O Martinez, ML Shaw… - Journal of …, 2006 - Am Soc Microbiol
Ebola virus (EBOV) infection blocks cellular production of alpha/beta interferon (IFN-α/β)
and the ability of cells to respond to IFN-α/β or IFN-γ. The EBOV VP35 protein has previously …

Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins

MS Park, ML Shaw, J Munoz-Jordan, JF Cros… - Journal of …, 2003 - Am Soc Microbiol
We have generated a recombinant Newcastle disease virus (NDV) that expresses the green
fluorescence protein (GFP) in infected chicken embryo fibroblasts (CEFs). This virus is …

[HTML][HTML] Cellular proteins in influenza virus particles

ML Shaw, KL Stone, CM Colangelo, EE Gulcicek… - PLoS …, 2008 - journals.plos.org
Virions are thought to contain all the essential proteins that govern virus egress from the
host cell and initiation of replication in the target cell. It has been known for some time that …

[PDF][PDF] Transcription elongation can affect genome 3D structure

…, L Pache, I Marazzi, A García-Sastre, ML Shaw… - Cell, 2018 - cell.com
How transcription affects genome 3D organization is not well understood. We found that during
influenza A (IAV) infection, rampant transcription rapidly reorganizes host cell chromatin …