[HTML][HTML] Management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline

JD Chalmers, ML Crichton… - European respiratory …, 2021 - Eur Respiratory Soc
Introduction Hospitalised patients with coronavirus disease 2019 (COVID-19) as a result of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have a high …

Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations

…, F Blasi, WG Boersma, ML Crichton… - The Lancet …, 2022 - thelancet.com
Bronchiectasis refers to both a clinical disease and a radiological appearance that has multiple
causes and can be associated with a range of conditions. Disease heterogeneity and the …

[HTML][HTML] Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease

AJ Dicker, ML Crichton, EG Pumphrey… - Journal of Allergy and …, 2018 - Elsevier
Background Neutrophil extracellular traps (NETs) have been observed in the airway in
patients with chronic obstructive pulmonary disease (COPD), but their clinical and …

[HTML][HTML] Bronchiectasis in India: results from the European multicentre bronchiectasis audit and research collaboration (EMBARC) and respiratory research network of …

…, P Vasudev, K Dimakou, ML Crichton… - The Lancet Global …, 2019 - thelancet.com
Background Bronchiectasis is a common but neglected chronic lung disease. Most
epidemiological data are limited to cohorts from Europe and the USA, with few data from low-income …

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study

…, YH Giam, G Suarez-Cuartin, ML Crichton… - The lancet Respiratory …, 2021 - thelancet.com
Background Bronchiectasis is predominantly a neutrophilic inflammatory disease. There are
no established therapies that directly target neutrophilic inflammation because little is …

Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis

…, M Lonergan, L Jayaram, ML Crichton… - The lancet Respiratory …, 2019 - thelancet.com
Background Bronchiectasis guidelines recommend long-term macrolide treatment for patients
with three or more exacerbations per year without Pseudomonas aeruginosa infection. …

[HTML][HTML] Bronchiectasis in Europe: data on disease characteristics from the European Bronchiectasis registry (EMBARC)

JD Chalmers, E Polverino, ML Crichton… - The Lancet …, 2023 - thelancet.com
Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre studies
exploring the causes, severity, microbiology, and treatment of the disease across Europe…

The efficacy and safety of inhaled antibiotics for the treatment of bronchiectasis in adults: a systematic review and meta-analysis

IF Laska, ML Crichton, A Shoemark… - The lancet respiratory …, 2019 - thelancet.com
Background Although use of inhaled antibiotics is the standard of care in cystic fibrosis, there
is insufficient evidence to support use of inhaled antibiotics in patients with bronchiectasis …

Update June 2022: management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline

N Roche, ML Crichton, PC Goeminne… - European respiratory …, 2022 - Eur Respiratory Soc
Since the identification of SARS-CoV-2 at the end of 2019, the coronavirus disease 2019 (COVID-19)
pandemic has affected more than 410 million people worldwide and killed almost …

The impact of the COVID-19 pandemic on exacerbations and symptoms in bronchiectasis: a prospective study

ML Crichton, A Shoemark… - American journal of …, 2021 - atsjournals.org
The underlying mechanisms leading to bronchiectasis symptoms and exacerbations are
poorly understood. Recent data suggest that daily symptoms such as cough and sputum are …