Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule

…, PMJ McLaughlin, LMFH de Leij, MC Harmsen - The American journal of …, 2007 - Elsevier
The epithelial cell adhesion molecule (EpCAM, CD326) is a glycoprotein of ∼40 kd that was
originally identified as a marker for carcinoma, attributable to its high expression on rapidly …

Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice

MJ van Amerongen, MC Harmsen… - The American journal of …, 2007 - Elsevier
Macrophages have been suggested to be beneficial for myocardial wound healing. We
investigated the role of macrophages in myocardial wound healing by inhibition of macrophage …

A modular and supramolecular approach to bioactive scaffolds for tissue engineering

PYW Dankers, MC Harmsen, LA Brouwer… - Nature materials, 2005 - nature.com
Bioactive polymeric scaffolds are a prerequisite for the ultimate formation of functional
tissues. Here, we show that supramolecular polymers based on quadruple hydrogen bonding …

Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in …

MC Harmsen, PJ Swart, MP Béthune… - Journal of Infectious …, 1995 - academic.oup.com
Native and chemically derivatized proteins purified from serum and milk were assayed in
vitro to assess their inhibiting capacity on the cytopathic effect of human immunodeficiency …

Cellular and molecular dynamics in the foreign body reaction

DT Luttikhuizen, MC Harmsen, MJAV Luyn - Tissue engineering, 2006 - liebertpub.com
Intracorporally implanted materials, such as medical devices, will provoke the body to initiate
an in- flammatory reaction. This inflammatory reaction to implanted materials is known as …

Reactive oxygen species (ROS) in macrophage activation and function in diabetes

…, V Riabov, DM Mossel, T Sevastyanova, MC Harmsen… - Immunobiology, 2019 - Elsevier
In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This contributes
to the vascular complications of diabetes. Recent studies have shown that ROS formation …

Endothelial–mesenchymal transition in atherosclerosis

C Souilhol, MC Harmsen, PC Evans… - Cardiovascular …, 2018 - academic.oup.com
Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …

Frequent monitoring of Epstein-Barr virus DNA load in unfractionated whole blood is essential for early detection of posttransplant lymphoproliferative disease in high …

…, I Pronk, W van der Bij, MC Harmsen… - Blood, The Journal …, 2001 - ashpublications.org
Posttransplant lymphoproliferative disease (PTLD) is a frequent and severe Epstein-Barr
virus (EBV)–associated complication in transplantation recipients that is caused by iatrogenic …

Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress

…, CJ Zeebregts, G Krenning, MC Harmsen - Cardiovascular …, 2015 - academic.oup.com
Aims Neointimal hyperplasia is a common feature of fibro-proliferative vascular disease and
characterizes initial stages of atherosclerosis. Neointimal lesions mainly comprise smooth …

[HTML][HTML] IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner

…, N Huijkman, B van de Sluis, G Krenning, MC Harmsen - Immunobiology, 2013 - Elsevier
Endothelial to mesenchymal transition (EndMT) contributes to fibrotic diseases. The main
inducer of EndMT is TGFβ signaling. TGFβ2 is the dominant isoform in the physiological …