Measurements of exhaled nitric oxide in healthy subjects age 4 to 17 years

…, B Gaston, J De Jongste, MWH Pijnenburg… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Fractional exhaled nitric oxide (FE NO ) is used in monitoring of asthma.
OBJECTIVES: The aim of this multicenter study was to establish normal values of FE NO and …

Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial

MW Pijnenburg, EM Bakker, WC Hop… - American journal of …, 2005 - atsjournals.org
Rationale: Corticosteroids are the antiinflammatory treatment of choice in asthma. Treatment
guidelines are mainly symptom-driven but symptoms are not closely related to airway …

Monitoring asthma in children

MW Pijnenburg, E Baraldi, PLP Brand… - European …, 2015 - Eur Respiratory Soc
The goal of asthma treatment is to obtain clinical control and reduce future risks to the
patient. To reach this goal in children with asthma, ongoing monitoring is essential. While all …

Advances in understanding and reducing the burden of severe asthma in children

MW Pijnenburg, L Fleming - The Lancet Respiratory Medicine, 2020 - thelancet.com
Severe asthma in children is rare, accounting for only a small proportion of childhood asthma.
After addressing modifiable factors such as adherence to treatment, comorbidities, and …

[HTML][HTML] COVID-19 in children with underlying chronic respiratory diseases: survey results from 174 centres

…, A Zacharasiewicz, MWH Pijnenburg - ERJ Open …, 2020 - Eur Respiratory Soc
Background Early reports suggest that most children infected with severe acute respiratory
syndrome coronavirus 2 (“SARS-CoV-2”) have mild symptoms. What is not known is whether …

Monitoring childhood asthma: web-based diaries and the asthma control test

…, JC de Jongste, PJ Merkus, MW Pijnenburg - Journal of allergy and …, 2014 - Elsevier
Background Data from asthma diaries are frequently used as an end point in asthma studies;
however, data on the validity of Web-based diaries are scarce. Objectives First, we …

Childhood asthma: pathogenesis and phenotypes

MW Pijnenburg, U Frey, JC De Jongste… - European Respiratory …, 2022 - Eur Respiratory Soc
In the pathogenesis of asthma in children there is a pivotal role for a type 2 inflammatory
response to early life exposures or events. Interactions between infections, atopy, genetic …

Lung CT imaging in patients with bronchopulmonary dysplasia: a systematic review

…, IKM Reiss, L Duijts, MW Pijnenburg… - Pediatric …, 2016 - Wiley Online Library
Background Bronchopulmonary dysplasia (BPD) is a common respiratory complication of
preterm birth and associated with long‐term respiratory sequelae. Chest computed …

Monitoring strategies in children with asthma: a randomised controlled trial

…, WC Hop, JC de Jongste, PJ Merkus, MW Pijnenburg - Thorax, 2015 - thorax.bmj.com
Background Asthma guidelines recommend monitoring of asthma control. However, in a
substantial proportion of children, asthma is poorly controlled and the best monitoring strategy …

Daily ambulatory exhaled nitric oxide measurements in asthma

MW Pijnenburg, SE Floor, WC Hop… - Pediatric allergy and …, 2006 - Wiley Online Library
Exhaled NO (FENO) is a non‐invasive, validated marker for asthmatic airway inflammation.
Recently, a new hand‐held NO‐analyzer has been developed which makes it possible to …