The human CD5L/AIM-CD36 axis: a novel autophagy inducer in macrophages that modulates inflammatory responses
…, N Amézaga, G Aran, M Naranjo-Gómez, L Arias… - Autophagy, 2015 - Taylor & Francis
CD5L (CD5 molecule-like) is a secreted glycoprotein that participates in host response to
bacterial infection. CD5L influences the monocyte inflammatory response to the bacterial …
bacterial infection. CD5L influences the monocyte inflammatory response to the bacterial …
[HTML][HTML] Influence of gut microbiota on progression to tuberculosis generated by high fat diet-induced obesity in C3HeB/FeJ mice
L Arias, GA Goig, P Cardona, M Torres-Puente… - Frontiers in …, 2019 - frontiersin.org
The administration of a high fat content diet is an accelerating factor for metabolic syndrome,
impaired glucose tolerance, and early type 2 diabetes. The present study aims to assess …
impaired glucose tolerance, and early type 2 diabetes. The present study aims to assess …
The role of antibodies in tuberculosis diagnosis, prophylaxis and therapy: a review from the ESGMYC study group
Tuberculosis (TB) is still responsible for the deaths of >1 million people yearly worldwide,
and therefore its correct diagnosis is one of the key components of any TB eradication …
and therefore its correct diagnosis is one of the key components of any TB eradication …
[HTML][HTML] Protective effect of intestinal helminthiasis against tuberculosis progression is abrogated by intermittent food deprivation
C Garrido-Amaro, P Cardona, D Gassó, L Arias… - Frontiers in …, 2021 - frontiersin.org
Background Tuberculosis (TB) is still a major challenge for humankind. Because regions with
the highest incidence also have a high prevalence of helminthiasis and nutritional scarcity, …
the highest incidence also have a high prevalence of helminthiasis and nutritional scarcity, …
Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles
…, F Drobniewski, I Kontsevaya, L Arias… - Journal of …, 2021 - Wiley Online Library
The identification of individuals with null alleles enables studying how the loss of gene
function affects infection. We previously described a non‐functional variant in SIGLEC1, which …
function affects infection. We previously described a non‐functional variant in SIGLEC1, which …
Identification of the most vulnerable populations in the psychosocial sphere: a cross-sectional study conducted in Catalonia during the strict lockdown imposed against …
J Farrés, JL Ruiz, JM Mas, L Arias, MR Sarrias… - BMJ open, 2021 - bmjopen.bmj.com
Design and objectives A cross-sectional study to evaluate the impact of COVID-19 on the
psychosocial sphere in both the general population and healthcare workers (HCWs). Methods …
psychosocial sphere in both the general population and healthcare workers (HCWs). Methods …
[HTML][HTML] A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis
…, H Schultz, S Tyagi, H Soni, PJ Converse, L Arias… - PLoS …, 2018 - journals.plos.org
Despite the existence of the prophylactic Bacille Calmette-Guérin (BCG) vaccine, infection
by Mycobacterium tuberculosis (Mtb) remains a major public health issue causing up to 1.8 …
by Mycobacterium tuberculosis (Mtb) remains a major public health issue causing up to 1.8 …
[HTML][HTML] Cording Mycobacterium tuberculosis Bacilli Have a Key Role in the Progression towards Active Tuberculosis, Which is Stopped by Previous Immune …
Cording was the first virulence factor identified in Mycobacterium tuberculosis (Mtb). We aimed
to ascertain its role in the induction of active tuberculosis (TB) in the mouse strain C3HeB/…
to ascertain its role in the induction of active tuberculosis (TB) in the mouse strain C3HeB/…
[HTML][HTML] A longitudinal prospective study of active tuberculosis in a Western Europe setting: insights and findings
…, N Jové, N Gogichadze, K L. Fonseca, L Arias… - Infection, 2024 - Springer
Purpose This study investigates the potential of inflammatory parameters (IP), symptoms, and
patient-related outcome measurements as biomarkers of severity and their ability to predict …
patient-related outcome measurements as biomarkers of severity and their ability to predict …
[HTML][HTML] SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed …
L Arias, K Otwombe, Z Waja, N Tukvadze, T Korinteli… - Trials, 2023 - Springer
Background The duration and regimen of tuberculosis (TB) treatment is currently based
predominantly on whether the M. tuberculosis (Mtb) strain is drug-sensitive (DS) or multidrug-…
predominantly on whether the M. tuberculosis (Mtb) strain is drug-sensitive (DS) or multidrug-…