User profiles for Konstantinos Samitas

Konstantinos Samitas

Respiratory Medicine Specialist, Athens Chest Hospital
Verified email at bioacademy.gr
Cited by 2394

[HTML][HTML] Genetics and epigenetics in asthma

…, A Photiades, E Zervas, G Xanthou, K Samitas - International Journal of …, 2021 - mdpi.com
Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …

Vitamin-D in the immune system: genomic and non-genomic actions

AI Trochoutsou, V Kloukina, K Samitas… - Mini reviews in …, 2015 - ingentaconnect.com
More than thirty years ago functions of vitamin D other than its beneficial effects on calcium
homeostasis and bone metabolism have been identified, mainly in relation to its …

Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives

K Samitas, V Delimpoura, E Zervas… - European respiratory …, 2015 - Eur Respiratory Soc
Asthma is a disorder of the airways involving various inflammatory cells and mediators and
characterised by bronchial hyperresponsiveness, chronic inflammation and structural …

[HTML][HTML] An algorithmic approach for the treatment of severe uncontrolled asthma

E Zervas, K Samitas, AI Papaioannou… - ERJ open …, 2018 - Eur Respiratory Soc
A small subgroup of patients with asthma suffers from severe disease that is either partially
controlled or uncontrolled despite intensive, guideline-based treatment. These patients have …

T2-low asthma: current approach to diagnosis and therapy

K Samitas, E Zervas, M Gaga - Current opinion in pulmonary …, 2017 - journals.lww.com
Asthma pathogenesis is characterized by two major endotypes, a T2-high featuring
increased eosinophilic airway inflammation, and a T2-low endotype presenting with either …

ERS/EAACI statement on severe exacerbations in asthma in adults: facts, priorities and key research questions

…, A Papi, RJ Russell, D Ryan, K Samitas… - European respiratory …, 2019 - Eur Respiratory Soc
Despite the use of effective medications to control asthma, severe exacerbations in asthma
are still a major health risk and require urgent action on the part of the patient and physician …

[HTML][HTML] Exhaled cysteinyl-leukotrienes and 8-isoprostane in patients with asthma and their relation to clinical severity

K Samitas, D Chorianopoulos, S Vittorakis, E Zervas… - Respiratory …, 2009 - Elsevier
BACKGROUND: Collection of exhaled breath condensate (EBC) is a safe, non-invasive
method to collect droplets of the airway surface liquid and measure mediators of airway …

[HTML][HTML] Targeting NLRP3 inflammasome activation in severe asthma

…, M Semitekolou, I Morianos, K Samitas… - Journal of clinical …, 2019 - mdpi.com
Severe asthma (SA) is a chronic lung disease characterized by recurring symptoms of
reversible airflow obstruction, airway hyper-responsiveness (AHR), and inflammation that is …

TFEB signaling attenuates NLRP3‐driven inflammatory responses in severe asthma

E Theofani, M Semitekolou, K Samitas, A Mais… - Allergy, 2022 - Wiley Online Library
Background NLRP3‐driven inflammatory responses by circulating and lung‐resident
monocytes are critical drivers of asthma pathogenesis. Autophagy restrains NLRP3‐induced …

Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses

…, TM Brodie, N Poulos, K Samitas… - Proceedings of the …, 2017 - National Acad Sciences
Type 1 regulatory T (Tr1) cells play a pivotal role in restraining human T-cell responses
toward environmental allergens and protecting against allergic diseases. Still, the precise …