User profiles for Konstantinos Samitas
Konstantinos SamitasRespiratory Medicine Specialist, Athens Chest Hospital Verified email at bioacademy.gr Cited by 2394 |
[HTML][HTML] Genetics and epigenetics in asthma
Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
Vitamin-D in the immune system: genomic and non-genomic actions
AI Trochoutsou, V Kloukina, K Samitas… - Mini reviews in …, 2015 - ingentaconnect.com
More than thirty years ago functions of vitamin D other than its beneficial effects on calcium
homeostasis and bone metabolism have been identified, mainly in relation to its …
homeostasis and bone metabolism have been identified, mainly in relation to its …
Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives
K Samitas, V Delimpoura, E Zervas… - European respiratory …, 2015 - Eur Respiratory Soc
Asthma is a disorder of the airways involving various inflammatory cells and mediators and
characterised by bronchial hyperresponsiveness, chronic inflammation and structural …
characterised by bronchial hyperresponsiveness, chronic inflammation and structural …
[HTML][HTML] An algorithmic approach for the treatment of severe uncontrolled asthma
E Zervas, K Samitas, AI Papaioannou… - ERJ open …, 2018 - Eur Respiratory Soc
A small subgroup of patients with asthma suffers from severe disease that is either partially
controlled or uncontrolled despite intensive, guideline-based treatment. These patients have …
controlled or uncontrolled despite intensive, guideline-based treatment. These patients have …
T2-low asthma: current approach to diagnosis and therapy
Asthma pathogenesis is characterized by two major endotypes, a T2-high featuring
increased eosinophilic airway inflammation, and a T2-low endotype presenting with either …
increased eosinophilic airway inflammation, and a T2-low endotype presenting with either …
ERS/EAACI statement on severe exacerbations in asthma in adults: facts, priorities and key research questions
Despite the use of effective medications to control asthma, severe exacerbations in asthma
are still a major health risk and require urgent action on the part of the patient and physician …
are still a major health risk and require urgent action on the part of the patient and physician …
[HTML][HTML] Exhaled cysteinyl-leukotrienes and 8-isoprostane in patients with asthma and their relation to clinical severity
K Samitas, D Chorianopoulos, S Vittorakis, E Zervas… - Respiratory …, 2009 - Elsevier
BACKGROUND: Collection of exhaled breath condensate (EBC) is a safe, non-invasive
method to collect droplets of the airway surface liquid and measure mediators of airway …
method to collect droplets of the airway surface liquid and measure mediators of airway …
[HTML][HTML] Targeting NLRP3 inflammasome activation in severe asthma
…, M Semitekolou, I Morianos, K Samitas… - Journal of clinical …, 2019 - mdpi.com
Severe asthma (SA) is a chronic lung disease characterized by recurring symptoms of
reversible airflow obstruction, airway hyper-responsiveness (AHR), and inflammation that is …
reversible airflow obstruction, airway hyper-responsiveness (AHR), and inflammation that is …
TFEB signaling attenuates NLRP3‐driven inflammatory responses in severe asthma
E Theofani, M Semitekolou, K Samitas, A Mais… - Allergy, 2022 - Wiley Online Library
Background NLRP3‐driven inflammatory responses by circulating and lung‐resident
monocytes are critical drivers of asthma pathogenesis. Autophagy restrains NLRP3‐induced …
monocytes are critical drivers of asthma pathogenesis. Autophagy restrains NLRP3‐induced …
Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses
…, TM Brodie, N Poulos, K Samitas… - Proceedings of the …, 2017 - National Acad Sciences
Type 1 regulatory T (Tr1) cells play a pivotal role in restraining human T-cell responses
toward environmental allergens and protecting against allergic diseases. Still, the precise …
toward environmental allergens and protecting against allergic diseases. Still, the precise …