The efficient and precise delivery of siRNA to target cells is critical to successful gene therapy.
While novel nanomaterials enhance delivery efficiency, it still remains challenging for …

In situ amplification methods, such as hybridization chain reaction, are valuable tools for
mapping the spatial distribution and subcellular location of target analytes. However, the live-…

Nucleic acid-based nanodevices have been widely used in the fields of biosensing and
nanomedicine. Traditionally, the majority of these nanodevices were first constructed in vitro …

Nonenzymatic DNA catalytic amplification strategies have greatly benefited bioanalysis.
However, long period incubation is usually required due to its relatively low reaction rate and …

Long non‐coding RNA (lncRNA) H19 in tumors played important roles in various biological
processes. However, the biological role and molecular mechanism of H19 in breast cancer …

A sensitive ratiometric electrochemical readout was designed with an immunoreaction-triggered
DNA assembly for one-step, fast and flexible assay of protein biomarker. The sensing …

Galangin is an active pharmacological ingredient from propolis and Alpinia officinarum
Hance, and has been reported to have anti-cancer and antioxidative properties. Berberine, a …

This work proposes the concept of ratiometric electrochemical proximity assay (REPA), which
can be used for one-step, highly sensitive and selective detection of protein. The assay …

Nitrogen-rich heterocyclic compounds (NRHCs) are an emerging type of explosive, and their
quantification is important in national security inspection and environmental monitoring. Up …

An electrochemical DNA biogate was designed for highly sensitive homogeneous
electrochemical immunoassay by combining target-induced proximity hybridization with a …