Mechanisms of activity-related dyspnea in pulmonary diseases

DE O'Donnell, J Ora, KA Webb, P Laveneziana… - Respiratory physiology …, 2009 - Elsevier
Progressive activity-related dyspnea dominates the clinical presentation of patients afflicted
by chronic obstructive and restrictive lung diseases. This symptom invariably leads to activity …

[HTML][HTML] Optimizing drug delivery in COPD: the role of inhaler devices

P Rogliani, L Calzetta, A Coppola, F Cavalli, J Ora… - Respiratory …, 2017 - Elsevier
Background Inhaled medication is the cornerstone of the pharmacological treatment for
patients with asthma and chronic obstructive pulmonary disease (COPD). Several inhaler …

[HTML][HTML] Adherence to COPD treatment: myth and reality

P Rogliani, J Ora, E Puxeddu, MG Matera… - Respiratory …, 2017 - Elsevier
COPD is a chronic disease in which effective management requires long-term adherence to
pharmacotherapies but the level of adhesion to the prescribed medications is very low and …

Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection

…, L Sarmati, N Cesta, M Iannetta, J Ora… - Brain, behavior, and …, 2020 - Elsevier
Objective Coronavirus disease 2019 (COVID-19) represents a novel pneumonia leading to
severe acute respiratory syndrome (SARS). Recent studies documented that SARS-…

Common mechanisms of dyspnea in chronic interstitial and obstructive lung disorders

…, AF Elbehairy, KA Webb, J Ora… - American journal of …, 2016 - atsjournals.org
Rationale: The mechanisms underlying dyspnea in interstitial lung disease (ILD) and chronic
obstructive pulmonary disease (COPD) are unknown. Objectives: To examine whether the …

Evolution of dyspnea during exercise in chronic obstructive pulmonary disease: impact of critical volume constraints

P Laveneziana, KA Webb, J Ora, K Wadell… - American journal of …, 2011 - atsjournals.org
Rationale: Patients with chronic obstructive pulmonary disease (COPD) primarily describe
their exertional dyspnea using descriptors alluding to increased effort or work of breathing …

Combined effects of obesity and chronic obstructive pulmonary disease on dyspnea and exercise tolerance

J Ora, P Laveneziana, D Ofir… - American journal of …, 2009 - atsjournals.org
Rationale: Severity of lung hyperinflation is known to influence the extent of dyspnea and
exercise intolerance among patients with chronic obstructive pulmonary disease (COPD) with …

Effect of obesity on respiratory mechanics during rest and exercise in COPD

J Ora, P Laveneziana, K Wadell… - Journal of Applied …, 2011 - journals.physiology.org
The presence of obesity in COPD appears not to be a disadvantage with respect to dyspnea
and weight-supported cycle exercise performance. We hypothesized that one explanation …

[HTML][HTML] Pharmacological characterisation of the interaction between glycopyrronium bromide and indacaterol fumarate in human isolated bronchi, small airways and …

M Cazzola, L Calzetta, E Puxeddu, J Ora, F Facciolo… - Respiratory …, 2016 - Springer
Background Nowadays, there is a considerable gap in knowledge concerning the mechanism(s)
by which long-acting β 2 -agonists (LABAs) and long-acting muscarinic antagonists (…

Airflow obstruction: is it asthma or is it COPD?

P Rogliani, J Ora, E Puxeddu… - International journal of …, 2016 - Taylor & Francis
Despite the availability of guideline recommendations, diagnostic confusion between COPD
and asthma appears common, and often it is very difficult to decide whether the obstruction …