Changes in liver histopathology in women infected with hepatitis C through contaminated anti-D immunoglobulin injections in Ireland

…, G Callagy, MG Courtney, JC O'Keane… - European journal of …, 1998 - journals.lww.com
Objective: To evaluate histological findings in untreated chronic hepatitis C patients at diagnosis
17 years after infection and to assess histological progression on repeat liver biopsy 2 …

[HTML][HTML] Gene expression profiling of naive sheep genetically resistant and susceptible to gastrointestinal nematodes

OM Keane, A Zadissa, T Wilson, DL Hyndman… - BMC genomics, 2006 - Springer
John C McEwan … The reactions were denatured at 94C for 3 minutes then cycled 36 times
at 94C for 45 sec, 55C for 45 sec and 72C for 60 sec. Finally products were extended at 72…

Microarray analysis of selection lines from outbred populations to identify genes involved with nematode parasite resistance in sheep

C Diez-Tascón, OM Keane, T Wilson… - Physiological …, 2005 - journals.physiology.org
Gastrointestinal nematodes infect sheep grazing contaminated pastures. Traditionally, these
have been controlled with anthelmintic drenching. The selection of animals resistant to …

Differentiating pulmonary cavities

C O'Connell, MA Aziz, JC O'Keane… - European …, 2013 - Eur Respiratory Soc
We present the case of a patient with pulmonary cavitation of extremely unusual aetiology,
which presented a significant diagnostic challenge despite multidisciplinary involvement. A 54…

Transcriptional profiling of Ovis aries identifies Ovar-DQA1 allele frequency differences between nematode-resistant and susceptible selection lines

OM Keane, KG Dodds, AM Crawford… - Physiological …, 2007 - journals.physiology.org
Gastrointestinal nematodes are a major cause of disease in grazing livestock; however,
individual animals differ in their response to infection. To identify genes whose expression …

Risk factors for, and genetic association with, intestinal atresia in dairy calves

OM Keane, TR Carthy, JP Hanrahan… - Animal …, 2023 - Wiley Online Library
Intestinal atresia is an under‐diagnosed congenital defect in cattle. It results in complete
occlusion of the intestinal lumen and, unless surgically corrected, results in death or euthanasia …

Fibrogenesis in Crohn's disease

JP Burke, JJ Mulsow, C O'keane… - Official journal of the …, 2007 - journals.lww.com
METHODS The electronic literature (January 1966 to May 2006) on CD-associated fibrosis
was reviewed. Further references were obtained by cross-referencing from key articles. …

[HTML][HTML] The role of HPV in determining treatment, survival, and prognosis of head and neck squamous cell carcinoma

…, E O'Regan, M Toner, E Kay, P Faul, C O'Keane… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC) incidence has been
escalating in the last two decades, particularly in Western Europe and North America. Human …

Two-year outcome of vagus nerve stimulation in treatment-resistant depression

…, C Frick, A Zobel, W Maier, V O'Keane… - Journal of clinical …, 2010 - journals.lww.com
One of the major goals of antidepressant treatment is a sustained response and remission of
depressive symptoms. Some of the previous studies of vagus nerve stimulation (VNS) have …

Polymorphisms in tumour necrosis factor‐α, transforming growth factor‐β, interleukin‐10, interleukin‐6, interferon‐γ, and outcome of hepatitis C virus infection

…, M Collins, C Kenny, E Ryan, CO Keane… - Journal of medical …, 2003 - Wiley Online Library
Cytokines play a key role in the regulation of immune responses. In hepatitis C virus
infection (HCV), the production of inappropriate cytokine levels appears to contribute to viral …