Previous studies showed that coculture of primary chondrocytes (PCs) with various sources
of multipotent cells results in a higher relative amount of cartilage matrix formation than …

Bioprinting is the most convenient microfabrication method to create biomimetic three‐dimensional
(3D) cardiac tissue constructs, that can be used to regenerate damaged tissue and …

Biochemically modified proteins have attracted significant attention due to their widespread
applications as biomaterials. For instance, chemically modified gelatin derivatives have been …

Developing biomimetic cartilaginous tissues that support locomotion while maintaining
chondrogenic behavior is a major challenge in the tissue engineering field. Specifically, while …

Cardiovascular diseases are prevalent worldwide and are the most frequent causes of death
in the United States. Although spending in drug discovery/development has increased, the …

Adverse immune reactions prevent clinical translation of numerous implantable devices and
materials. Although inflammation is an essential part of tissue regeneration, chronic …

Recent years have seen tremendous advances in the field of hydrogel-based biomaterials.
One of the most prominent revolutions in this field has been the integration of elements or …

Objective The development of osteoarthritis (OA) may be caused by activation of hypertrophic
differentiation of articular chondrocytes. Healthy articular cartilage is highly resistant to …

Actively steering the chondrogenic differentiation of mesenchymal stromal cells (MSCs) into
either permanent cartilage or hypertrophic cartilage destined to be replaced by bone has not …

Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-based
therapy and for tissue regeneration in particular. Recent evidence indicates that the main …