A free radical is any molecule that has an odd number of electrons. Free radicals, which can
occur in both organic (ie, quinones) and inorganic molecules (ie, O (2)), are highly reactive …

… Clyde BL, Chang LY, Auten RL, Ho YS, Crapo JD. Distribution of manganese superoxide
dismutase mRNA in normal and hyperoxic rat lung. Am J Respir Cell Mol Biol 1993;8:530–537. …

There is ample evidence that allergic disorders, such as asthma, rhinitis, and atopic dermatitis,
are mediated by oxidative stress. Excessive exposure to reactive oxygen and nitrogen …

Background: COPDGene is a multicenter observational study designed to identify genetic
factors associated with COPD. It will also characterize chest CT phenotypes in COPD subjects, …

This report is to complement the original Fleischner Society recommendations for incidentally
detected solid nodules by proposing a set of recommendations specifically aimed at …

Eight normal human lungs obtained from patients dying from causes not related to the lung
were subjected to morphometric analysis to determine the number of cells in the alveolar …

We performed a genome-wide association study of non-Hispanic, white individuals with fibrotic
idiopathic interstitial pneumonias (IIPs; n = 1,616) and controls (n = 4,683), with follow-up …

An increased production of oxygen radicals has been postulated to be a major factor in the
etiology of lung damage during hyperoxia. Mitochondrial electron transport was inhibited with …

The lungs of rats exposed to 100 % O 2 until death and to 85 % O 2 for as long as 14 days
were studied using morphometric and biochemical techniques. The primary injury leading to …

Publisher Summary This chapter discusses the preparation and assay of superoxide
dismutase (SOD). SODs are found in all oxygen-utilizing organisms and constitute a defense …