The main aim of this international consensus document on obstructive sleep apnea is to provide
guidelines based on a critical analysis of the latest literature to help health professionals …

Rationale: Obstructive sleep apnea and systemic hypertension (SH) are highly prevalent.
Although their association has been suggested in cross-sectional studies, conflicting evidence …

Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED) is a neurological
condition with an overall prevalence in adults of 5-10% in Europe and North America. It is …

Background Evidence from longitudinal studies has reported contradictory results regarding
the association between OSA and hypertension. In a previous analysis of the Vitoria Sleep …

Obstructive sleep apnea (OSA) is characterized by repetitive episodes of upper airway
obstruction caused by a loss of upper airway dilator muscle tone during sleep and an inadequate …

Objectives Recent animal models of restless legs syndrome (RLS) suggest that brain iron
deficiency is associated with a hypoadenosinergic state, with downregulation of adenosine A 1 …

Background OSA has been associated with increased incidence and aggressiveness of
melanoma. However, the long-term impact of OSA and CPAP treatment on the prognosis of …

Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is a common
neurological disorder affecting up to 5% to 10% of the population, but it remains an …

The goal of this study was to assess the relationship between the severity of obstructive sleep
apnoea (OSA) and the levels of carcinogenesis- and tumour growth-related biomarkers in …

Obstructive sleep apnoea (OSA) upregulates the programmed cell death-1 receptor and its
ligand (PD-L1) pathway, potentially compromising immunosurveillance. We compared …