Background Pathological features of the airway in young children with severe recurrent
wheeze suggest an association between bacterial colonization and the initiating events of early …

Background We hypothesized that asthma is preceded by a stage of recurrent episodes of
wheezing during the first years of life and that inhaled corticosteroid therapy during …

BACKGROUND: Fractional exhaled nitric oxide (FE NO ) is used in monitoring of asthma.
OBJECTIVES: The aim of this multicenter study was to establish normal values of FE NO and …

This document provides recommendations for monitoring and treatment of children in whom
bronchopulmonary dysplasia (BPD) has been established and who have been discharged …

Background Use of maintenance antibiotic therapy with the macrolide azithromycin is
increasing in a number of chronic respiratory disorders including primary ciliary dyskinesia (PCD). …

Objectives To describe the development of atopic dermatitis (AD) during the first 3 years of
life and identify the localization of the early skin lesions that predicts the development of AD. …

Background The lung clearance index (LCI) derived from the multiple breath inert gas washout
(MBW) test reflects global ventilation distribution inhomogeneity. It is more sensitive than …

The use of pulmonary function tests (PFTs) has been widely described in airway diseases
like asthma and cystic fibrosis, but for children's interstitial lung disease (chILD), which …

Background Hypersensitivity pneumonitis is a rare interstitial lung disease and very few
data regarding frequency, treatment and outcome exist for children. Children identified with …

Background Clinical management of primary ciliary dyskinesia (PCD) respiratory disease is
currently based on improving mucociliary clearance and controlling respiratory infections, …