ContextThe pathogenesis of high-altitude pulmonary edema (HAPE) is considered an
altered permeability of the alveolar-capillary barrier secondary to intense pulmonary …

Swenson, Erik R. Hypoxic pulmonary vasoconstriction. High Alt Med Biol 14:101–110, 2013.—Hypoxic
pulmonary vasoconstriction (HPV) continues to fascinate cardiopulmonary …

Key Clinical Points Acute High-Altitude Illnesses Acute high-altitude illnesses occur in persons
who are not acclimatized during the first days at an altitude of 2500 m or higher, with wide …

At any point 1–5 days following ascent to altitudes ≥2500 m, individuals are at risk of
developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of …

During the ongoing coronavirus disease (COVID-19) pandemic, reports in social media and
the lay press indicate that a subset of patients are presenting with severe hypoxemia in the …

Background Appropriate interpretation of pulmonary function tests (PFTs) involves the
classification of observed values as within/outside the normal range based on a reference …

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of any publisher or professional medical society. This document has not been endorsed by …

High-altitude pulmonary edema (HAPE) develops in rapidly ascending nonacclimatized
healthy individuals at altitudes above 3,000 m. An excessive rise in pulmonary artery pressure (…

Background— Pulmonary hypertension (PH) is associated with increased morbidity across
the cardiopulmonary disease spectrum. Based primarily on expert consensus opinion, PH is …

To minimize transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the novel coronavirus responsible for coronavirus disease (COVID-19), the US Centers for …