Background: Dyspnea is a common, distressing symptom of cardiopulmonary and neuromuscular
diseases. Since the ATS published a consensus statement on dyspnea in 1999, there …

The role of dynamic hyperinflation (DH) in exercise limitation in chronic obstructive pulmonary
disease (COPD) remains to be defined. We examined DH during exercise in 105 patients …

Study Design All subjects were previously thoroughly familiarized with exercise testing
protocols and breathlessness ratings. Subjects were instructed to refrain from using …

Changes in lung hyperinflation, dyspnea, and exercise endurance are important outcomes
in assessing therapeutic responses in chronic obstructive pulmonary disease (COPD). …

We wished to determine which resting spirometric parameters best reflect improvements in
exercise tolerance and exertional dyspnea in response to acute high-dose anticholinergic …

Chronic obstructive pulmonary disease (COPD) is a major respiratory illness in Canada that
is both preventable and treatable. Our understanding of the pathophysiology of this complex …

… Correspondence and requests for reprints should be addressed to Denis E. O'Donnell,
MD, FRCP(I), FRCP(C), Division of Respiratory and Critical Care Medicine, Respiratory …

We compared qualitative aspects of the sensory experience of exertional breathlessness in
normal subjects and in patients with chronic airflow limitation (CAL) and sought a physiologic …

Effective management of dyspnea in chronic obstructive pulmonary disease (COPD) requires
a clearer understanding of its underlying mechanisms. This roundtable reviews what is …

Rationale: Smokers with a relatively preserved FEV 1 may experience dyspnea and activity
limitation but little is known about underlying mechanisms. Objectives: To examine …