User profiles for David G. Chapman
David G ChapmanUniversity of Technology Sydney Verified email at uts.edu.au Cited by 1873 |
Mechanisms of airway hyper‐responsiveness in asthma: the past, present and yet to come
DG Chapman, CG Irvin - Clinical & Experimental Allergy, 2015 - Wiley Online Library
Airway hyper‐responsiveness ( AHR ) has long been considered a cardinal feature of
asthma. The development of the measurement of AHR 40 years ago initiated many important …
asthma. The development of the measurement of AHR 40 years ago initiated many important …
The nonallergic asthma of obesity. A matter of distal lung compliance
A Al-Alwan, JHT Bates, DG Chapman… - American journal of …, 2014 - atsjournals.org
Rationale: The pathogenesis of asthma in obesity is poorly understood, but may be related
to breathing at low lung volumes. Objectives: To determine if lung function in obese patients …
to breathing at low lung volumes. Objectives: To determine if lung function in obese patients …
Maternal e-cigarette exposure in mice alters DNA methylation and lung cytokine expression in offspring
E-cigarette usage is increasing, especially among the young, with both the general population
and physicians perceiving them as a safe alternative to tobacco smoking. Worryingly, e-…
and physicians perceiving them as a safe alternative to tobacco smoking. Worryingly, e-…
The evolving landscape of e-cigarettes: a systematic review of recent evidence
J Bozier, EK Chivers, DG Chapman, AN Larcombe… - Chest, 2020 - Elsevier
Smoking continues to be a burden to economies and health-care systems across the world.
One proposed solution to the problem has been e-cigarettes; however, because they are a …
One proposed solution to the problem has been e-cigarettes; however, because they are a …
Reducing protein oxidation reverses lung fibrosis
Idiopathic pulmonary fibrosis is characterized by excessive deposition of collagen in the
lung, leading to chronically impaired gas exchange and death 1 , 2 – 3 . Oxidative stress is …
lung, leading to chronically impaired gas exchange and death 1 , 2 – 3 . Oxidative stress is …
[HTML][HTML] JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers
…, Y Ye, JD Nolin, SM Hoffman, DG Chapman… - Clinical and translational …, 2016 - Springer
Background Lung remodeling and pulmonary fibrosis are serious, life-threatening conditions
resulting from diseases such as chronic severe asthma and idiopathic pulmonary fibrosis (…
resulting from diseases such as chronic severe asthma and idiopathic pulmonary fibrosis (…
Peripheral airway dysfunction and relationship with symptoms in smokers with preserved spirometry
…, C Thamrin, CS Farah, A Bertolin, DG Chapman… - …, 2018 - Wiley Online Library
Background and objective Smokers develop respiratory symptoms and peripheral airway
dysfunction even when spirometry is preserved. Multiple breath nitrogen washout (MBNW) and …
dysfunction even when spirometry is preserved. Multiple breath nitrogen washout (MBNW) and …
Influence of distinct asthma phenotypes on lung function following weight loss in the obese
DG Chapman, CG Irvin, DA Kaminsky… - …, 2014 - Wiley Online Library
Background and objective There appears to be two distinct clinical phenotypes of obese
patients with asthma—those with early‐onset asthma and high serum IgE ( T H 2 ‐high), and …
patients with asthma—those with early‐onset asthma and high serum IgE ( T H 2 ‐high), and …
Animal models of allergic airways disease: where are we and where to next?
DG Chapman, JE Tully, JD Nolin… - Journal of cellular …, 2014 - Wiley Online Library
In a complex inflammatory airways disease such as asthma, abnormalities in a plethora of
molecular and cellular pathways ultimately culminate in characteristic impairments in …
molecular and cellular pathways ultimately culminate in characteristic impairments in …
[HTML][HTML] The effect of flavored e-cigarettes on murine allergic airways disease
DG Chapman, DT Casey, JL Ather, M Aliyeva… - Scientific reports, 2019 - nature.com
Flavored e-cigarettes are preferred by the majority of users yet their potential toxicity is
unknown. Therefore our aim was to determine the effect of selected flavored e-cigarettes, with or …
unknown. Therefore our aim was to determine the effect of selected flavored e-cigarettes, with or …