Smoking is one of the major lifestyle factors influencing the health of human beings. Life-long
cigarette smokers have a higher prevalence of common diseases such as atherosclerosis …

COPD is a multicomponent disease characterized by abnormal inflammatory response of the
lungs to noxious particles that is accompanied by systemic effects like weight loss, muscle …

Background Elevated circulating levels of C-reactive protein (CRP), interleukin (IL)-6 and
fibrinogen (FG) have been repeatedly associated with many adverse outcomes in patients with …

The purpose of this study was to investigate the possible roles of the genes functioning in
xenobiotic metabolism and antioxidant pathways in the development of severe chronic lung …

Cigarette smoking is the main risk factor for developing the inflammatory lung disease chronic
obstructive pulmonary disease (COPD). Differences in susceptibility among smokers have …

Our studies have shown that the genotype and allele frequencies of polymorphisms G(−1607)GG
of MMP1 gene, C(−1562)T of MMP9 gene, and A(−82)G of MMP12 gene do not …

Polymorphism of GSTM1 and GSTP1 genes was studied in patients with cystic fibrosis (CF)
and chronic bronchopulmonary diseases (CBPD) living in Bashkortostan. A combination of …

To assess the role that polymorphisms of cytokine genes play in genetic predisposition to
chronic obstructive pulmonary disease (COPD), the allele and genotype distributions of IL1B, …

Frequencies of CYP1A1, CYP2E1, and mEPHX polymorphic variants were analyzed in cystic
fibrosis, chronic obstructive lung disease, bronchiectatic disease, chronic nonobstructive …

Genetic polymorphism of xenobiotic metabolizing enzymes responsible for individual
susceptibility to different environmental factors was examined in a cohort of petrochemical workers …