Importance Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that
was first reported in Wuhan, China, and has subsequently spread worldwide. Risk factors for …

The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular
endothelia and aquaporin-4 (AQP4) in airway epithelia. To test whether these water channels …

Despite substantial progress in reducing the global impact of many non-communicable
diseases, including heart disease and cancer, morbidity and mortality due to chronic respiratory …

An ongoing outbreak of 2019-nCoV pneumonia was first identified in Wuhan, Hubei province,
China at the end of 2019. With the spread of the new coronavirus accelerating, person-to-…

In 2008, lung cancer replaced liver cancer as the number one cause of death among people
with malignant tumors in China. The registered lung cancer mortality rate increased by …

Background Although exposure to cigarette smoking and air pollution is common, the current
prevalence of chronic obstructive pulmonary disease (COPD) is unknown in the Chinese …

Background Asthma is a common chronic airway disease worldwide. Despite its large
population size, China has had no comprehensive study of the national prevalence, risk factors, …

Background Icotinib, an oral EGFR tyrosine kinase inhibitor, had shown antitumour activity
and favourable toxicity in early-phase clinical trials. We aimed to investigate whether icotinib …

Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic
factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a …

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a syndrome characterized
by pulmonary edema and acute inflammation. Lipopolysaccharide (LPS), a major …