Pulmonary fibrosis from molecular mechanisms to therapeutic interventions: lessons from post-COVID-19 patients

…, R Piccarducci, L Marchetti, C Romei… - Biochemical …, 2021 - Elsevier
Pulmonary fibrosis (PF) is characterised by several grades of chronic inflammation and
collagen deposition in the interalveolar space and is a hallmark of interstitial lung diseases (ILDs)…

Prognostic value of lung ultrasound B-lines in systemic sclerosis

L Gargani, C Bruni, C Romei, P Frumento, A Moreo… - Chest, 2020 - Elsevier
Background A high percentage of systemic sclerosis (SSc) patients experience interstitial
lung disease (ILD) during the disease course. Recent data have shown that lung ultrasound (…

[HTML][HTML] The A2B Adenosine Receptor Modulates the Epithelial– Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in …

C Giacomelli, S Daniele, C Romei, L Tavanti… - Frontiers in …, 2018 - frontiersin.org
The epithelial-mesenchymal transition (EMT) is a complex process in which cell phenotype
switches from the epithelial to mesenchymal one. The deregulations of this process have …

[HTML][HTML] The use of chest magnetic resonance imaging in interstitial lung disease: a systematic review

C Romei, L Turturici, L Tavanti… - European …, 2018 - Eur Respiratory Soc
Thin-slices multi-detector computed tomography (MDCT) plays a key role in the differential
diagnosis of interstitial lung disease (ILD). However, thin-slices MDCT has a limited ability to …

[HTML][HTML] Low-dose CT for lung cancer screening: Position paper from the Italian college of thoracic radiology

…, AV Marchianò, S Palmucci, L Preda, C Romei… - La radiologia …, 2022 - Springer
Smoking is the main risk factor for lung cancer (LC), which is the leading cause of cancer-related
death worldwide. Independent randomized controlled trials, governmental and inter-…

Automated computed tomography analysis in the assessment of idiopathic pulmonary fibrosis severity and progression

C Romei, LM Tavanti, A Taliani, A De Liperi… - European Journal of …, 2020 - Elsevier
Chiara Romei has made substantial contributions to conception and design, acquisition of
data, analysis and interpretation of data; has drafted the submitted article, revised it critically …

[HTML][HTML] Integrating liquid biopsy and radiomics to monitor clonal heterogeneity of EGFR-positive non-small cell lung cancer

F Cucchiara, M Del Re, S Valleggi, C Romei… - Frontiers in …, 2020 - frontiersin.org
Background EGFR-positive Non-small Cell Lung Cancer (NSCLC) is a dynamic entity and
tumor progression and resistance to tyrosine kinase inhibitors (TKIs) arise from the …

Combining liquid biopsy and radiomics for personalized treatment of lung cancer patients. State of the art and new perspectives

F Cucchiara, I Petrini, C Romei, S Crucitta… - Pharmacological …, 2021 - Elsevier
Lung cancer has become a paradigm for precision medicine in oncology, and liquid biopsy (LB)
together with radiomics may have a great potential in this scenario. They are both …

[HTML][HTML] Impact of the COVID-19 pandemic on the selection of chest imaging modalities and reporting systems: a survey of Italian radiologists

…, S Palmucci, I Pulzato, C Rampinelli, C Romei… - La radiologia …, 2021 - Springer
Purpose Chest imaging modalities play a key role for the management of patient with
coronavirus disease (COVID-19). Unfortunately, there is no consensus on the optimal chest …

[HTML][HTML] Low diaphragm muscle mass predicts adverse outcome in patients hospitalized for COVID-19 pneumonia: an exploratory pilot study.

…, G Santori, G Barbieri, C Romei… - Minerva …, 2021 - pesquisa.bvsalud.org
BACKGROUND: The aim of this study was to evaluate whether measurement of diaphragm
thickness (DT) by ultrasonography may be a clinically useful noninvasive method for …