User profiles for Bruna Rubbo
Bruna RubboVerified email at soton.ac.uk Cited by 874 |
[HTML][HTML] Nurse staffing levels and patient outcomes: a systematic review of longitudinal studies
Background The contribution of registered nurses towards safe patient care has been
demonstrated in many studies. However, most of the evidence linking staffing levels to outcomes is …
demonstrated in many studies. However, most of the evidence linking staffing levels to outcomes is …
Topological data analysis reveals genotype–phenotype relationships in primary ciliary dyskinesia
A Shoemark, B Rubbo, M Legendre… - European …, 2021 - Eur Respiratory Soc
Background Primary ciliary dyskinesia (PCD) is a heterogeneous inherited disorder caused
by mutations in approximately 50 cilia-related genes. PCD genotype–phenotype …
by mutations in approximately 50 cilia-related genes. PCD genotype–phenotype …
[HTML][HTML] Accuracy of high-speed video analysis to diagnose primary ciliary dyskinesia
Background Diagnosis of primary ciliary dyskinesia (PCD) relies on a combination of tests.
High-speed video microscopy analysis (HSVA) is widely used to contribute to the diagnosis. It …
High-speed video microscopy analysis (HSVA) is widely used to contribute to the diagnosis. It …
Diagnosing primary ciliary dyskinesia: an international patient perspective
Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by progressive sino-pulmonary
disease, with symptoms starting soon after birth. A European Respiratory …
disease, with symptoms starting soon after birth. A European Respiratory …
[HTML][HTML] The association between multi-disciplinary staffing levels and mortality in acute hospitals: a systematic review
Objectives Health systems worldwide are faced with the challenge of adequately staffing their
hospital services. Much of the current research and subsequent policy has been focusing …
hospital services. Much of the current research and subsequent policy has been focusing …
[HTML][HTML] Use of electronic health records to ascertain, validate and phenotype acute myocardial infarction: a systematic review and recommendations
Electronic health records (EHRs) offer the opportunity to ascertain clinical outcomes at large
scale and low cost, thus facilitating cohort studies, quality of care research and clinical trials. …
scale and low cost, thus facilitating cohort studies, quality of care research and clinical trials. …
High prevalence of CCDC103 p. His154Pro mutation causing primary ciliary dyskinesia disrupts protein oligomerisation and is associated with normal diagnostic …
Rationale Primary ciliary dyskinesia is a genetically heterogeneous inherited condition
characterised by progressive lung disease arising from abnormal cilia function. Approximately …
characterised by progressive lung disease arising from abnormal cilia function. Approximately …
[HTML][HTML] Clinical care for primary ciliary dyskinesia: current challenges and future directions
Primary ciliary dyskinesia (PCD) is a rare genetic disease that affects the motility of cilia,
leading to impaired mucociliary clearance. It is estimated that the vast majority of patients with …
leading to impaired mucociliary clearance. It is estimated that the vast majority of patients with …
[HTML][HTML] The Effects of Methionine Acquisition and Synthesis on Streptococcus Pneumoniae Growth and Virulence
Bacterial pathogens need to acquire nutrients from the host, but for many nutrients their
importance during infection remain poorly understood. We have investigated the importance of …
importance during infection remain poorly understood. We have investigated the importance of …
Risk factors for situs defects and congenital heart disease in primary ciliary dyskinesia
Primary ciliary dyskinesia (PCD) is associated with abnormal organ positioning (situs) and
congenital heart disease (CHD). This study investigated genotype–phenotype associations in …
congenital heart disease (CHD). This study investigated genotype–phenotype associations in …