Reactive nitrogen species in the respiratory tract

FLM Ricciardolo, A Di Stefano, F Sabatini… - European journal of …, 2006 - Elsevier
Endogenous Nitric Oxide (NO) plays a key role in the physiological regulation of airway
functions. In response to various stimuli activated inflammatory cells (eg, eosinophils and …

Cytokine inhibition in the treatment of COPD

G Caramori, IM Adcock, A Di Stefano… - International journal of …, 2014 - Taylor & Francis
Cytokines play an important part in many pathobiological processes of chronic obstructive
pulmonary disease (COPD), including the chronic inflammatory process, emphysema, and …

[HTML][HTML] COPD immunopathology

…, A Barczyk, AL Durham, A Di Stefano… - Seminars in …, 2016 - Springer
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …

Phospho-p38 MAPK expression in COPD patients and asthmatics and in challenged bronchial epithelium

…, B Balbi, IM Adcock, G Caramori, A Di Stefano - Respiration, 2015 - karger.com
Background: The role of mitogen-activated protein kinases (MAPK) in regulating the inflammatory
response in the airways of patients with chronic obstructive pulmonary disease (COPD…

CD8+ T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease

M Saetta, A Di STEFANO, G Turato… - American journal of …, 1998 - atsjournals.org
To investigate whether the inflammatory process in peripheral airways is different in
smokers who develop symptoms of chronic bronchitis and chronic airflow limitation and in …

Severity of airflow limitation is associated with severity of airway inflammation in smokers

A DI STEFANO, A Capelli, M LUSUARDI… - American journal of …, 1998 - atsjournals.org
To investigate the relationship between airflow limitation and airway inflammation in smokers,
we examined paraffin-embedded bronchial biopsies obtained from 30 smokers: 10 with …

Airway eosinophilia in chronic bronchitis during exacerbations.

M Saetta, A Di Stefano, P Maestrelli… - American journal of …, 1994 - atsjournals.org
To examine the nature and the degree of airway inflammation in chronic bronchitis during
exacerbations, bronchial biopsies and sputum were obtained in 11 subjects with chronic …

Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis

M Saetta, A Di Stefano, P Maestrelli… - American review of …, 1993 - atsjournals.org
To examine the nature and the degree of leukocyte infiltration and to determine the state of
activation of cells in bronchial mucosa of subjects with chronic bronchitis, bronchoscopy was …

Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma

M Saetta, A Di Stefano, C Rosina, G Thiene… - Am Rev Respir …, 1991 - atsjournals.org
The peripheral airways and the adjacent muscular pulmonary arteries were studied by
morphometric methods in the autopsy lungs of six asthmatic subjects who died suddenly during …

Isolation and characterization of Oct-4+/HLA-G+ mesenchymal stem cells from human umbilical cord matrix: differentiation potential and detection of new markers

…, F Magno, T Loria, M Lo Iacono, A Di Stefano… - Histochemistry and cell …, 2009 - Springer
The presence of multipotent cells in several adult and embryo-related tissues opened new
paths for their use in regenerative medicine. Extraembryonic tissues such as umbilical cord …