These guidelines incorporate the recent advances in chronic cough pathophysiology, diagnosis
and treatment. The concept of cough hypersensitivity has allowed an umbrella term that …

… Correspondence and requests for reprints should be addressed to Professor Alyn H.
Morice, MD, FRCP, Department of Academic Medicine, University of Hull, Castle Hill Hospital, …

Background Gefapixant is a P2X3 receptor antagonist that has shown promise for the treatment
of refractory and unexplained chronic cough. The aim of this study was to evaluate the …

Recent evidence supports a beneficial effect of testosterone on the cardiovascular system.
Testosterone acts as a coronary vasodilator and reduces myocardial ischemia in men with …

Our understanding of the relationship between gastro-oesophageal reflux and respiratory
disease has recently undergone important changes. The previous paradigm of airway reflux …

The enduring impact of COVID-19 on patients has been examined in recent studies, leading
to the description of Long-COVID. We report the lasting symptom burden of COVID-19 …

Study objective To assess whether the breath carbon monoxide (CO) concentration can be
used to determine a patient's smoking habits in a respiratory outpatient clinic. Design To …

Background Gefapixant is an oral P2X 3 receptor antagonist that has previously shown efficacy
and safety in refractory chronic cough and unexplained chronic cough. We therefore aim …

Cough is an essential defence mechanism [1]. However, chronic cough is a significant
cause of morbidity, seriously impairing quality of life [2]. Previously, chronic cough was …

In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …