User profiles for Alexander Moeller

Alexander Moeller

University children's hospital zuerich
Verified email at kispi.uzh.ch
Cited by 5336

[HTML][HTML] Tezacaftor–ivacaftor in patients with cystic fibrosis homozygous for Phe508del

…, EF McKone, CK Van Der Ent, A Moeller… - New england journal …, 2017 - Mass Medical Soc
Background Combination treatment with the cystic fibrosis transmembrane conductance
regulator (CFTR) modulators tezacaftor (VX-661) and ivacaftor (VX-770) was designed to target …

European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years

…, O Yilmaz, A Zacharasiewicz, A Moeller - European respiratory …, 2021 - Eur Respiratory Soc
Background Diagnosing asthma in children represents an important clinical challenge. There
is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-…

[HTML][HTML] Integrin α3 Mutations with Kidney, Lung, and Skin Disease

…, G Spartā, D Kiritsi, L Weibel, A Moeller… - … England Journal of …, 2012 - Mass Medical Soc
<p id="p001">Integrin α<sub>3</sub> is a transmembrane integrin receptor subunit that
mediates signals between the cells and their microenvironment. We identified three patients …

On-Line Analysis of Exhaled Breath: Focus Review

…, B Streckenbach, S Müller, A Moeller… - Chemical …, 2019 - ACS Publications
On-line analysis of exhaled breath offers insight into a person’s metabolism without the
need for sample preparation or sample collection. Due to its noninvasive nature and the …

Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells

…, E Kieninger, A Jung, A Moeller… - European …, 2015 - Eur Respiratory Soc
Virus-associated pulmonary exacerbations, often associated with rhinoviruses (RVs),
contribute to cystic fibrosis (CF) morbidity. Currently, there are only a few therapeutic options to …

Monitoring asthma in children

…, MJ Mäkelä, E Mantzouranis, A Moeller… - European …, 2015 - Eur Respiratory Soc
The goal of asthma treatment is to obtain clinical control and reduce future risks to the
patient. To reach this goal in children with asthma, ongoing monitoring is essential. While all …

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function …

…, R Brugha, S Gartner, J Legg, A Moeller… - American journal of …, 2022 - atsjournals.org
Rationale: The triple-combination regimen elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA)
was shown to be safe and efficacious in children aged 6 through 11 years with cystic fibrosis …

Monitoring asthma in childhood: lung function, bronchial responsiveness and inflammation

A Moeller, KH Carlsen, PD Sly, E Baraldi… - European …, 2015 - Eur Respiratory Soc
This review focuses on the methods available for measuring reversible airways obstruction,
bronchial hyperresponsiveness (BHR) and inflammation as hallmarks of asthma, and their …

[HTML][HTML] COVID-19 in children with underlying chronic respiratory diseases: survey results from 174 centres

A Moeller, L Thanikkel, L Duijts, EA Gaillard… - ERJ Open …, 2020 - Eur Respiratory Soc
Background Early reports suggest that most children infected with severe acute respiratory
syndrome coronavirus 2 (“SARS-CoV-2”) have mild symptoms. What is not known is whether …

Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37

…, C Tapparel, A Jung, A Moeller… - European respiratory …, 2016 - Eur Respiratory Soc
Vitamin D has immunomodulatory properties in the defence against pathogens. Its insufficiency
is a widespread feature of cystic fibrosis (CF) patients, which are repeatedly suffering …