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Page 1
Pathogenesis of pulmonary arterial hypertension: lessons from cancer.
Guignabert C, Tu L, Le Hiress M, Ricard N, Sattler C, Seferian A, Huertas A, Humbert M, Montani D. Guignabert C, et al. Among authors: le hiress m. Eur Respir Rev. 2013 Dec;22(130):543-51. doi: 10.1183/09059180.00007513. Eur Respir Rev. 2013. PMID: 24293470 Free PMC article. Review.
Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension.
Guignabert C, Phan C, Seferian A, Huertas A, Tu L, Thuillet R, Sattler C, Le Hiress M, Tamura Y, Jutant EM, Chaumais MC, Bouchet S, Manéglier B, Molimard M, Rousselot P, Sitbon O, Simonneau G, Montani D, Humbert M. Guignabert C, et al. Among authors: le hiress m. J Clin Invest. 2016 Sep 1;126(9):3207-18. doi: 10.1172/JCI86249. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482885 Free PMC article. Clinical Trial.
Design, Synthesis, and Biological Activity of New N-(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension.
Le Hiress M, Akagah B, Bernadat G, Tu L, Thuillet R, Huertas A, Phan C, Fadel E, Simonneau G, Humbert M, Jalce G, Guignabert C. Le Hiress M, et al. J Med Chem. 2018 Apr 12;61(7):2725-2736. doi: 10.1021/acs.jmedchem.7b01312. Epub 2018 Mar 19. J Med Chem. 2018. PMID: 29526099
Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension.
Ricard N, Tu L, Le Hiress M, Huertas A, Phan C, Thuillet R, Sattler C, Fadel E, Seferian A, Montani D, Dorfmüller P, Humbert M, Guignabert C. Ricard N, et al. Among authors: le hiress m. Circulation. 2014 Apr 15;129(15):1586-97. doi: 10.1161/CIRCULATIONAHA.113.007469. Epub 2014 Jan 30. Circulation. 2014. PMID: 24481949