The prevalence of hypercalcaemia in pulmonary and miliary tuberculosis--a longitudinal study

Singapore Med J. 1994 Dec;35(6):613-5.

Abstract

We studied the prevalence of hypercalcaemia in 34 Chinese patients with pulmonary (n = 32) or miliary (n = 2) tuberculosis. None of these subjects were given vitamin D or calcium supplements. Plasma calcium levels were measured at presentation and at 1- to 2-monthly intervals after treatment. During the 6-month study period, two patients (6%) developed hypercalcaemia (plasma calcium greater than 2.51 mmol/l), as compared to figures of 16% to 28% in the United States and India. By correcting the plasma calcium to a normal albumin, five (15%) of our patients were hypercalcaemic, as compared to a figure of 48% in Greece. Apart from variations in methodology, discrepancies in the reported prevalence of hypercalcaemia in tuberculosis may be due to differences in sun exposure, and vitamin D and calcium intake.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Calcium, Dietary
  • China / ethnology
  • Female
  • Hong Kong / epidemiology
  • Humans
  • Hypercalcemia / blood
  • Hypercalcemia / epidemiology
  • Hypercalcemia / microbiology*
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Prevalence
  • Tuberculosis, Miliary / complications*
  • Tuberculosis, Miliary / ethnology
  • Tuberculosis, Pulmonary / complications*
  • Tuberculosis, Pulmonary / ethnology

Substances

  • Calcium, Dietary