The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer

Peter Goldstraw; Kari Chansky; John Crowley; Ramon Rami-Porta; Hisao Asamura; Wilfried E E Eberhardt; Andrew G Nicholson; Patti Groome; Alan Mitchell; Vanessa Bolejack; International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Boards, and Participating Institutions; International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee Advisory Boards and Participating Institutions

doi:10.1016/j.jtho.2015.09.009

The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer

J Thorac Oncol. 2016 Jan;11(1):39-51. doi: 10.1016/j.jtho.2015.09.009.

Authors

Collaborators

Peter Goldstraw, Ramón Rami-Porta, Hisao Asamura, David Ball, David G Beer, Ricardo Beyruti, Vanessa Bolejack, Kari Chansky, John Crowley, Frank Detterbeck, Wilfried Ernst Erich Eberhardt, John Edwards, Françoise Galateau-Sallé, Dorothy Giroux, Fergus Gleeson, Patti Groome, James Huang, Catherine Kennedy, Jhingook Kim, Young Tae Kim, Laura Kingsbury, Haruhiko Kondo, Mark Krasnik, Kaoru Kubota, Antoon Lerut, Gustavo Lyons, Mirella Marino, Edith M Marom, Jan van Meerbeeck, Alan Mitchell, Takashi Nakano, Andrew G Nicholson, Anna Nowak, Michael Peake, Thomas Rice, Kenneth Rosenzweig, Enrico Ruffini, Valerie Rusch, Nagahiro Saijo, Paul Van Schil, Jean-Paul Sculier, Lynn Shemanski, Kelly Stratton, Kenji Suzuki, Yuji Tachimori, Charles F Thomas Jr, William Travis, Ming S Tsao, Andrew Turrisi, Johan Vansteenkiste, Hirokazu Watanabe, Yi-Long Wu, Paul Baas, Jeremy Erasmus, Seiki Hasegawa, Kouki Inai, Kemp Kernstine, Hedy Kindler, Lee Krug, Kristiaan Nackaerts, Harvey Pass, David Rice, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, Kazuya Kondo, Marco Lucchi, Meinoshin Okumura, Eugene Blackstone, F Abad Cavaco, E Ansótegui Barrera, J Abal Arca, I Parente Lamelas, A Arnau Obrer, R Guijarro Jorge, D Ball, G K Bascom, A I Blanco Orozco, M A González Castro, M G Blum, D Chimondeguy, V Cvijanovic, S Defranchi, B de Olaiz Navarro, I Escobar Campuzano, I Macía Vidueira, E Fernández Araujo, F Andreo García, K M Fong, G Francisco Corral, S Cerezo González, J Freixinet Gilart, L García Arangüena, S García Barajas, P Girard, T Goksel, M T González Budiño, G González Casaurrán, J A Gullón Blanco, J Hernández Hernández, H Hernández Rodríguez, J Herrero Collantes, M Iglesias Heras, J M Izquierdo Elena, E Jakobsen, S Kostas, P León Atance, A Núñez Ares, M Liao, M Losanovscky, G Lyons, R Magaroles, L De Esteban Júlvez, M Mariñán Gorospe, B McCaughan, C Kennedy, R Melchor Íñiguez, L Miravet Sorribes, S Naranjo Gozalo, C Álvarez de Arriba, M Núñez Delgado, J Padilla Alarcón, J C Peñalver Cuesta, J S Park, H Pass, M J Pavón Fernández, M Rosenberg, E Ruffini, V Rusch, J Sánchez de Cos Escuín, A Saura Vinuesa, M Serra Mitjans, T E Strand, D Subotic, S Swisher, R Terra, C Thomas, K Tournoy, P Van Schil, M Velasquez, Y L Wu, K Yokoi

Affiliations

¹ Department of Thoracic Surgery, Royal Brompton and Harefield National Health Service Foundation Trust and Imperial College, London, United Kingdom. Electronic address: p.goldstraw@imperiaL.ac.uk.
² Cancer Research and Biostatistics, Seattle, WA, USA.
³ Department of Thoracic Surgery, Hospital Universitari Mutua Terrassa, University of Barcelona, and CIBERES Lung Cancer Group, Terrassa, Barcelona, Spain.
⁴ Division of Thoracic Surgery, Keio University School of Medicine, Tokyo, Japan.
⁵ West German Cancer Centre, University Hospital, Ruhrlandklinik, University Duisburg-Essen, Essen, Germany.
⁶ Department of Pathology, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, United Kingdom.
⁷ Queen's Cancer Research Institute, Kingston, ON, Canada.

PMID: 26762738
DOI: 10.1016/j.jtho.2015.09.009

Abstract

The IASLC Staging and Prognostic Factors Committee has collected a new database of 94,708 cases donated from 35 sources in 16 countries around the globe. This has now been analysed by our statistical partners at Cancer Research And Biostatistics and, in close collaboration with the members of the committee proposals have been developed for the T, N, and M categories of the 8th edition of the TNM Classification for lung cancer due to be published late 2016. In this publication we describe the methods used to evaluate the resultant Stage groupings and the proposals put forward for the 8th edition.

Keywords: Lung cancer; Prognostic factors; Staging.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Lung Neoplasms / classification*
Lung Neoplasms / pathology*
Neoplasm Staging / standards*
Prognosis
SEER Program