Abstract
Primary infection with Mycobacterium tuberculosis usually occurs during childhood. The source of infection is most often an adult. The risk of infection in exposed children is modulated by various factors related to the infectiousness of the index case, exposure conditions, and the child himself. This review aims to describe the specific diagnostic and therapeutic features of latent TB infection and TB disease in childhood.
Copyright © 2011 SPLF. Published by Elsevier Masson SAS. All rights reserved.
MeSH terms
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Acute Disease
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Adolescent
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Antitubercular Agents / adverse effects
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Antitubercular Agents / therapeutic use
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Child
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Child, Preschool
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Disease Progression
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Drug Therapy, Combination
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Humans
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Infant
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Infant, Newborn
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Latent Tuberculosis / diagnosis
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Latent Tuberculosis / drug therapy
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Latent Tuberculosis / transmission
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Risk Factors
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Tuberculosis Vaccines / administration & dosage
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Tuberculosis, Pulmonary / diagnosis*
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Tuberculosis, Pulmonary / drug therapy
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Tuberculosis, Pulmonary / prevention & control
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Tuberculosis, Pulmonary / transmission
Substances
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Antitubercular Agents
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Tuberculosis Vaccines