A case of cardiopulmonary bilharziasis is studied in a female, 21 years old, from Senegal, infested by Schistosoma haematobium. With praziquantel, the patient was cured in 16 months. The cardiopulmonary bilharziasis is more frequent on pathological examination than in clinical features. The diagnosis of cardiopulmonary bilharziasis is made by pulmonary biopsy which shows an occlusive angiitis with chronic inflammatory cells, and arteriolar medial hypertrophy. The prognosis is dependent upon development to schistosomal cor pulmonale and right ventricular failure. The newly developed drugs are effect in cardiopulmonary bilharziasis, in experimental studies.