Abstract
Pneumococcal nasopharyngeal carriage, serotype distribution, and penicillin-susceptibility were monitored among children attending daycare centers in France from 1999 to 2006 to assess the impact of pneumococcal conjugate vaccine and antibiotic-reducing policies. Pneumococcal carriage remained stable. Immunization rates reached 68% in 2006. Serotype distribution shifted significantly from vaccine serotypes to vaccine-related and nonvaccine serotypes. Antibiotic treatments fell by 50%.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Carrier State / epidemiology*
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Child Day Care Centers*
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Child, Preschool
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Cross-Sectional Studies
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Female
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France / epidemiology
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Heptavalent Pneumococcal Conjugate Vaccine
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Humans
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Infant
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Male
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Meningococcal Vaccines
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Microbial Sensitivity Tests
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Nasopharynx / microbiology*
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Penicillin Resistance
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Pneumococcal Infections / epidemiology*
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Pneumococcal Vaccines
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Serotyping
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Streptococcus pneumoniae / classification
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Streptococcus pneumoniae / isolation & purification*
Substances
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Heptavalent Pneumococcal Conjugate Vaccine
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Meningococcal Vaccines
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Pneumococcal Vaccines