Abstract
The Snail superfamily of zinc-finger transcription factors is involved in processes that imply pronounced cell movements, both during embryonic development and in the acquisition of invasive and migratory properties during tumour progression. Different family members have also been implicated in the signalling cascade that confers left right identity, as well as in the formation of appendages, neural differentiation, cell division and cell survival.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amino Acid Sequence
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Animals
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Cell Division
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Cell Survival
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Chick Embryo
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Conserved Sequence
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DNA-Binding Proteins / classification
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DNA-Binding Proteins / genetics
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DNA-Binding Proteins / physiology*
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Gene Expression Regulation, Developmental
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Humans
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Mice
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Models, Biological
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Molecular Sequence Data
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Phylogeny
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Repressor Proteins / genetics
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Repressor Proteins / physiology
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Sequence Homology, Amino Acid
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Signal Transduction
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Snail Family Transcription Factors
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Transcription Factors / classification
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Transcription Factors / genetics
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Transcription Factors / physiology*
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Zinc Fingers / genetics
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Zinc Fingers / physiology
Substances
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DNA-Binding Proteins
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Repressor Proteins
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Snail Family Transcription Factors
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Transcription Factors