Chest
Volume 128, Issue 2, August 2005, Pages 1018-1021
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Roentgenogram of the Month
A 73-Year-Old Woman With a Cough

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Discussion

Bronchocentric granulomatosis was first described by Liebow in 19731 and describes a rare granulomatous process centered on the bronchi and bronchioles. While the etiology of bronchocentric granulomatosis is uncertain, it has been postulated that it is a hypersensitivity reaction to endobronchial Aspergillus, as Aspergillus species have been cultured from the tissue specimens in a significant percentage of all cases, 75% of cases in one series.2 The typical histopathologic features of

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