Chest
Clinical Investigations: Sleep and BreathingPrevalence of Sleep-Disordered Breathing in Diastolic Heart Failure
Section snippets
Subjects
Subjects were recruited from the cardiology outpatient clinic in our hospital with symptoms of heart failure (New York Heart Association class II or III). The diagnosis of hypertension was based on BP readings of >140/90 mm Hg on three separate occasions prior to commencement of treatment with antihypertensive medications. Those who had normal systolic function (LVEF >50%) and diastolic dysfunction on two-dimensional echocardiogram and Doppler studies were selected. Patients were receiving
Results
Thirteen male and seven female patients were evaluated (mean age = 65±6.0 years; mean body mass index [BMI]=28±3.2). Seventeen of 20 patients (85%) had a diagnosis of hypertension. As a group, the mean BP recorded on hospital admission was 136±10/83±8 mm Hg. Based on the Likert scale, more than half of the patients reported significant symptoms related to sleep apnea such as heavy snoring, excessive daytime somnolence, and nocturnal awakenings. The mean scores on the Likert scale were as
Discussion
We have shown that SDB, in particular OSA, was common in a group of patients with symptomatic DHF. Hypertension, the most common cause of DHF, was present in a large proportion (85%) of our patients. The association between SDB and essential hypertension is firmly established. Among patients with OSA, 40 to 60% had hypertension.13 Among unselected hypertensive patients, OSA was found with a prevalence of 30 to 50%.14 Confounding risk factors for both hypertension and SDB such as obesity, age,
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