Chest
Original ResearchPneumoniaDecrease in Long-term Survival for Hospitalized Patients With Community-Acquired Pneumonia
Section snippets
Study Design and Study Population
This was a retrospective, observational study of a cohort of adult patients admitted to the Veterans Affairs Medical Center of Louisville, Kentucky, from June 1, 2001, to November 26, 2006. Patients were included into the study if they were admitted to the hospital for any medical condition. Patients admitted for surgical conditions or psychiatric conditions were excluded. This cohort was divided into two groups: group 1, CAP(+), were patients hospitalized with a diagnosis of CAP during the
Results
From a total of 6,971 patients, definitive CAP was identified in 624 patients (9%). Characteristics of CAP(+) and CAP(−) patients are shown in Table 1. CAP(+) patients were more likely to be elderly (67% vs 49%, P < .0001) and have a higher mCCI (2.0 vs 1.4, P < .0001) as compared with CAP(−) patients.
The Kaplan-Meier survival curve comparing CAP(+) vs CAP(−) showed a progressive decline in survival of both groups of patients (Fig 1). The survival was significantly lower among CAP(+) patients
Discussion
In this study, we documented a significant decrease in survival for hospitalized patients with CAP over a 7.5-year average follow-up. This shorter survival of patients with CAP remained significant after adjustment for age and comorbidities when compared with patients hospitalized during the same period of time for medical problems other than CAP.
Our study design and results have some differences from others previously reported.3, 4, 5, 6, 8, 9, 10, 11 Our study included a comorbidity index
Acknowledgments
Author contributions: All authors provided critical revision of the manuscript and final approval for publication.
Dr Bordon: contributed to study concept and design, interpretation, drafting of the manuscript, and study supervision.
Mr Wiemken: contributed to statistical analysis, interpretation, and drafting of the manuscript.
Dr Peyrani: contributed to interpretation and drafting of the manuscript.
Dr Paz: contributed to data collection.
Dr Gnoni: contributed to data collection.
Dr Cabral:
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