Chest
Original ResearchSleep MedicineOutcomes of Home-Based Diagnosis and Treatment of Obstructive Sleep Apnea
Section snippets
Subjects
Adult outpatients with suspected OSA referred to the participating sleep medicine physicians (R. P. S., J. R., B. M.) at a tertiary outpatient sleep disorders clinic were eligible to take part in the study. The inclusion criteria were: age > 18 years, symptoms of OSA (at least two of the following: excessive daytime somnolence (Epworth Sleepiness Scale [ESS] > 10), witnessed apneas, snoring), and residence within a 1-h drive from the study center. Exclusion criteria were: respiratory or heart
Results
The study flow chart is presented in Figure 1. Two hundred and seventy consecutive adult patients referred to the outpatient sleep disorders clinic at the University of Saskatchewan, Saskatoon, Canada, with suspected OSA were screened. One hundred and two met the inclusion criteria and were randomized (age, 47.4 ± 11.4 years; 63 men; BMI, 32.3 ± 6.3 kg/m2; ESS, 12.5 ± 4.3; systolic BP, 131.0 ± 16 mm Hg; diastolic BP, 85 ± 9 mm Hg). There was no difference in age, sex distribution, BMI, and ESS
Discussion
Our study results indicate that in-laboratory diagnosis and therapy for OSA, using primarily a split-night PSG, does not lead to superior 4-week outcomes (subjective somnolence, arterial BP, sleep quality, and quality of life) when compared with home-based diagnosis and treatment. Patients suspected to have OSA who were randomized to diagnosis and therapy at home had similar improvements in subjective sleepiness, quality of life scores, and arterial BP after 4 weeks of CPAP therapy.
Acknowledgments
Author contributions: Dr Skomro: participated in the study design, subject recruitment, data analysis, and manuscript preparation and review.
Dr Gjevre: participated in the study design, subject recruitment, data analysis, and manuscript preparation and review.
Dr Reid: participated in the study design, subject recruitment, data analysis, and manuscript preparation and review.
Dr McNab: participated in the study design, subject recruitment, data analysis, and manuscript preparation and review.
Dr
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Funding/Support: The financial support for this study was provided by the Kelsey Trail Health Region, the Lung Association of Saskatchewan, and Saskatoon Health Region.
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