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Left and right ventriculo-arterial coupling in a patient with congenitally corrected transposition

Published online by Cambridge University Press:  18 November 2005

Pierre Wauthy ,
Robert Naeije  and
Serge Brimioulle
Pierre Wauthy
Affiliation:
Department of Cardiac Surgery, Brugmann Hospital, Brussels, Belgium
Robert Naeije
Affiliation:
Department of Physiology, Erasme Hospital, Free University of Brussels, Brussels, Belgium
Serge Brimioulle
Affiliation:
Department of Intensive Care, Erasme Hospital, Free University of Brussels, Brussels, Belgium
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Abstract

The single beat method was used to evaluate right and left ventriculo-arterial coupling in an asymptomatic patient with congenitally corrected transposition. The ratio of ventricular end-systolic to arterial elastances was normal for the left ventricle coupled to the pulmonary circulation, and depressed for the right ventricle coupled to the systemic circulation. This result suggests that chronic uncoupling of the right ventricle to the systemic circulation might play a role in the pathophysiology produced by congenitally corrected transposition.

Keywords

Congenital heart diseaseheart failureright ventricle
Type
Brief Report
Information
Cardiology in the Young , Volume 15 , Issue 6 , December 2005 , pp. 647 - 649
Copyright
© 2005 Cambridge University Press

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References

Kuehne T, Yilmaz S, Steendijk P, et al. Magnetic resonance imaging analysis of right ventricular pressure-volume loops: in vivo validation and clinical application in patients with pulmonary hypertension. Circulation 2004; 110: 2010–2016.Google Scholar
Graham Jr TP, Parrish MD, Boucek Jr RJ, et al. Assessment of ventricular size and function in congenitally corrected transposition of the great arteries. Am J Cardiol 1983; 51: 244–251.Google Scholar
Brimioulle S, Wauthy P, Ewalenko P, et al. Single-beat estimation of right ventricular end-systolic pressure-volume relationship. Am J Physiol Heart Circ Physiol 2003; 284: H1625–H1630.Google Scholar
Wauthy P, Pagnamenta A, Vassalli F, Naeije R, Brimioulle S. Right ventricular adaptation to pulmonary hypertension: an interspecies comparison. Am J Physiol Heart Circ Physiol 2004; 286: H1441–H1447.Google Scholar
Rondelet B, Kerbaul F, Motte S, et al. Bosentan for the prevention of overcirculation-induced experimental pulmonary arterial hypertension. Circulation 2003; 107: 1329–1335.Google Scholar
Burkhoff D, Sagawa K. Ventricular efficiency predicted by an analytical model. Am J Physiol 1986; 250: R1021–R1027.Google Scholar
Maughan WL, Shoukas AA, Sagawa K, Weisfeldt ML. Instantaneous pressure-volume relationship of the canine right ventricle. Circ Res 1979; 44: 309–315.Google Scholar
Sagawa K. The end-systolic pressure-volume relation of the ventricle: definition, modifications and clinical use. Circulation 1981; 63: 1223–1227.Google Scholar
Redington AN, Rigby ML, Shinebourne EA, Oldershaw PJ. Changes in the pressure-volume relation of the right ventricle when its loading conditions are modified. Br Heart J 1990; 63: 45–49.Google Scholar
Asanoi H, Sasayama S, Kameyama T. Ventriculoarterial coupling in normal and failing heart in humans. Circ Res 1989; 65: 483–493.Google Scholar