Thoracic transplantationEight Years of Lung Transplantation: Experience of the National Research Institute of Tuberculosis and Lung Diseases
Section snippets
Patients and Methods
The study included data for all patients who underwent lung transplantation, as well as those on the waiting list, collected from 2000 to 2008. Data included patient age and sex, underlying disease, date of transplantation procedure, type of transplant (single or bilateral), ABO blood group, cytomegalovirus seropositivity of donor and recipient, and results of transplantation. At our center, indications and contraindications for lung transplantation are consistent with widely accepted criteria.2
Results
Approximately 170 patients were listed for lung transplantation during the 8-year study. The cause of end-stage pulmonary disease was bronchiectasis in 37.0%, chronic obstructive pulmonary disease in 24.7%, pulmonary fibrosis in 22.1%, and primary pulmonary hypertension in 16.2%. Mean time on the waiting list is about 2 years; 25% of patients in the list die each year, and only 2% to 4% undergo lung transplantation.
Of our 24 patients, the underlying lung diseases were pulmonary fibrosis
Discussion
Lung transplantation is one of the most difficult medical practices because of patient preparation, the surgical procedure, and postoperative care. As a result, there are fewer lung transplantation centers compared with other organ transplantation centers.
Approximately 17 to 30 patients come to the hospital transplant clinic weekly. Because of the shortage of donors, both the number of candidates awaiting transplantation and the number of patients who die while on waiting list are increasing.
In
References (11)
- et al.
Technique of successful clinical double lung transplantation
Ann Thorac Surg
(1988) - et al.
Low doses of mycophenolate mofetil with low doses of tacrolimus prevent acute rejection and long-term function loss after lung transplantation
Transplant Proc
(2001) - et al.
Costs and outcomes of prolonged cytomegalovirus prophylaxis to cover the enhanced immunosuppression phase following lung transplantation
Chest
(1999) - et al.
The past, present and future of lung transplantation
Am J Surg
(1997) - et al.
International Society for Heart and Lung Transplantation, the American Thoracic Society of Transplant Physicians, the European Respiratory Society: International guidelines for the selection of lung transplant candidates
J Heart Lung Transplant
(2007)
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A case of single lung transplantation for alveolar microlithiasis combined with pneumothorax
2020, Zhonghua Jiehe he Huxi Zazhi / Chinese Journal of Tuberculosis and Respiratory DiseasesPulmonary alveolar microlithiasis
2020, European Respiratory ReviewSingle-lung transplantation for pulmonary alveolar microlithiasis: A case report
2019, World Journal of Clinical Cases