ReviewPhysiological and pathological regulation of ACE2, the SARS-CoV-2 receptor
Graphical abstract
Chemical compounds studied in this article
Diminazene aceturate (PubChem CID: 5284544)
Resorcinolnaphthalein (PubChem CID: 337218)
Xanthenone (PubChem CID: 7020)
Abbreviations
ACE2
angiotensin-converting enzyme 2
ACEI
ACE inhibitor
Ang
angiotensin
ARB
angiotensin II receptor blocker
ARDS
acute respiratory distress syndrome
AT2
type II apical surface of epithelial cells
COPD
chronic obstructive pulmonary disease
COVID-19
Coronavirus disease 2019
DIC
disseminated intravascular coagulopathy
HIF-1α
hypoxia-inducible factor-1α
hrsACE2
human recombinant soluble ACE2
PAH
pulmonary arterial hypertension
rACE2
recombinant ACE2
RAS
renin-angiotensin system
SARS-CoV
severe acute respiratory syndrome coronavirus
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
Keywords
Angiotensin-converting enzyme 2
Severe acute respiratory syndrome coronavirus 2
Coronavirus disease 2019
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These authors contributed equally to the manuscript.
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