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Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4

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M.C. is a recipient of the Next Generation Young Researcher Support Program from Seoul National University. A part of this study was supported by the Post-genome Program of the National Research Foundation funded by the Ministry of Science, ICT & Future Planning (grant no. NRF-2014M3C9A2064686; to M.C.), the Seoul National University Hospital Research Fund (grant no. 04-2012-1020 to J.S.M.), the Korean Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea (grant no. HI14C1466), and the Integrative Aging Research Center at Gwangju Institute of Science and Technology (to S.G.P.).

Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest.

These authors contributed equally to this work.