Developmental Cell
Volume 18, Issue 4, 20 April 2010, Pages 675-685
ResourceResolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst
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Highlights
► Robust methodology for single cell gene expression analysis in early embryos ► Zygotic activation of Sox2 occurs in inner cells of the morula ► Fgf4/Fgfr2 inverse correlation evident within the early inner cell mass ► Fgf signaling precedes the primitive endoderm transcriptional program
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These authors contributed equally to this work
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Present address: Department of Obstetrics and Gynecology, Nanjing Maternal and Child Health Care Hospital, Nanjing Medical University, Nanjing 210004, China
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