Congenital heart diseaseComparison of Echocardiographic and Cardiac Magnetic Resonance Imaging Measurements of Functional Single Ventricular Volumes, Mass, and Ejection Fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study)†
Section snippets
Methods
A detailed description of the design and inclusion and exclusion criteria of the Pediatric Heart Network Fontan Cross-Sectional Study has been published.2 Briefly, subjects aged 6 to 18 years were enrolled from March 2003 through April 2004 at 7 pediatric clinical centers in the United States and Canada. Prospective data collection for each subject occurred within a 3-month period and included health status questionnaires, 2-dimensional and Doppler echocardiography, CMR, exercise, and other
Results
The demographic, anatomic, and image quality data for the echocardiography and CMR groups are listed in Table 1. The groups were similar with respect to age, gender, race, and ventricular type.
Table 2 lists intra- and interobserver agreement for echocardiographic image quality and ventricular function grade. Although the confidence intervals (CIs) are wide, the data suggest that agreement for overall image quality grade was weak, with readers' assessments of quality being concordant less than
Discussion
The results of this study reveal several important findings regarding the noninvasive assessment of FSV size and function. Although the qualitative assessment of LV function by 2-dimensional echocardiography was moderately reproducible between observers, assessment of the right ventricle was poorly reproducible. In contrast, quantitative echocardiographic measures of ventricular volumes were quite reproducible for LV and RV morphologies. Although 2-dimensional echocardiographic measurements
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Cited by (0)
This study was supported by U01 grants HL068269, HL068270, HL068279, HL068281, HL068285, HL068292, HL068290, and HL068288 from the National Heart, Lung and Blood Institute, Bethesda, Maryland.