Cas cliniqueHypertension artérielle pulmonaire postembolique tumoralePulmonary arterial hypertension due to tumour emboli
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Cited by (16)
Pulmonary tumor thrombotic microangiopathy
2017, Revue des Maladies RespiratoiresPulmonary hypertension associated with chronic hemolytic anemia and other blood disorders
2013, Clinics in Chest MedicineCitation Excerpt :In patients with a high thrombotic risk, therapy with hydroxyurea is recommended.124 Precapillary PH mimicking PAH73,110,120,125–137: Several factors have been suggested for the pathogenesis of PAH in patients with CMPD: (1) Portal hypertension, which is a cause of PAH and is a well-known complication of myeloid metaplasia with myelofibrosis.138 ( 2) Chemotherapeutic agents or stem cell transplantation, both of which are treatment options for these conditions and have been associated with pulmonary venoocclusive disease.125 (
Classification of Pulmonary Hypertension
2012, Heart Failure ClinicsCitation Excerpt :Metastatic tumor microemboli are rare but can lead to rapidly progressive and fatal PH. Patients with this condition usually have a history of cancer (typically breast, lung, or gastric carcinomas) and are hypoxic on presentation, with clear lung fields on imaging and no evidence of pulmonary emboli on CT pulmonary angiography. Ventilation-perfusion scanning often shows abnormalities of perfusion, including diffusely heterogeneous perfusion abnormalities without segmental or subsegmental defects or multiple subsegmental ventilation-perfusion mismatches.161,162 Pulmonary microvascular blood aspiration via a pulmonary artery catheter in the wedge position with cytologic analysis for tumor cells can be diagnostic in these cases.
Atypical unilateral insterstitial disease
2011, Revue des Maladies RespiratoiresUpdated Clinical Classification of Pulmonary Hypertension
2009, Journal of the American College of CardiologyCitation Excerpt :Occlusion of the microvasculature by metastatic tumor emboli represents another rare cause of rapidly progressive PH (136). The initial laboratory evaluation shows hypoxemia, often severe, with a clear lung field (137). Computed tomography scanning does not show proximal thrombi but often shows thickening of septa.
Analysis of clinical index changes of right heart hypofunction in patients with primary myelofibrosis
2021, Journal of Leukemia and Lymphoma